Overview of host miRNA properties and their association with epigenetics, long non-coding RNAs, and Xeno-infectious factors

S Heydarzadeh, M Ranjbar, F Karimi, F Seif… - Cell & Bioscience, 2021 - Springer
MicroRNA-derived structures play impressive roles in various biological processes. So
dysregulation of miRNAs can lead to different human diseases. Recent studies have …

sRNAbench and sRNAtoolbox 2019: intuitive fast small RNA profiling and differential expression

E Aparicio-Puerta, R Lebrón, A Rueda… - Nucleic acids …, 2019 - academic.oup.com
Since the original publication of sRNAtoolbox in 2015, small RNA research experienced
notable advances in different directions. New protocols for small RNA sequencing have …

Dissecting heterogeneity in malignant pleural mesothelioma through histo-molecular gradients for clinical applications

Y Blum, C Meiller, L Quetel, N Elarouci, M Ayadi… - Nature …, 2019 - nature.com
Malignant pleural mesothelioma (MPM) is recognized as heterogeneous based both on
histology and molecular profiling. Histology addresses inter-tumor and intra-tumor …

[HTML][HTML] exceRpt: a comprehensive analytic platform for extracellular RNA profiling

J Rozowsky, RR Kitchen, JJ Park, TR Galeev, J Diao… - Cell systems, 2019 - cell.com
Small RNA sequencing has been widely adopted to study the diversity of extracellular RNAs
(exRNAs) in biofluids; however, the analysis of exRNA samples can be challenging: they are …

sRNAtoolbox: an integrated collection of small RNA research tools

A Rueda, G Barturen, R Lebrón… - Nucleic acids …, 2015 - academic.oup.com
Small RNA research is a rapidly growing field. Apart from microRNAs, which are important
regulators of gene expression, other types of functional small RNA molecules have been …

A review on recent computational methods for predicting noncoding RNAs

Y Zhang, H Huang, D Zhang, J Qiu… - BioMed research …, 2017 - Wiley Online Library
Noncoding RNAs (ncRNAs) play important roles in various cellular activities and diseases.
In this paper, we presented a comprehensive review on computational methods for ncRNA …

[HTML][HTML] Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients

MAJ van Eijndhoven, JM Zijlstra, NJ Groenewegen… - JCI insight, 2016 - ncbi.nlm.nih.gov
BACKGROUND. Cell-free circulating nucleic acids, including 22-nt microRNAs (miRNAs),
represent noninvasive biomarkers for treatment response monitoring of cancer patients …

[HTML][HTML] Non-invasive prostate cancer detection by measuring miRNA variants (isomiRs) in urine extracellular vesicles

D Koppers-Lalic, M Hackenberg, R De Menezes… - Oncotarget, 2016 - ncbi.nlm.nih.gov
In many cancer types, the expression and function of∼ 22 nucleotide-long microRNAs
(miRNA) is deregulated. Mature miRNAs can be stably detected in extracellular vesicles …

Integrated molecular characterization of chondrosarcoma reveals critical determinants of disease progression

R Nicolle, M Ayadi, A Gomez-Brouchet… - Nature …, 2019 - nature.com
Chondrosarcomas are primary cancers of cartilaginous tissue with highly contrasting
prognoses. These tumors are defined by recurrent mutations in the IDH genes and other …

sRNAnalyzer—a flexible and customizable small RNA sequencing data analysis pipeline

X Wu, TK Kim, D Baxter, K Scherler… - Nucleic acids …, 2017 - academic.oup.com
Although many tools have been developed to analyze small RNA sequencing (sRNA-Seq)
data, it remains challenging to accurately analyze the small RNA population, mainly due to …