HIV drug resistance in children and adolescents: always a challenge?
WLA Koay, J Kose-Otieno, N Rakhmanina - Current epidemiology reports, 2021 - Springer
Abstract Purpose of Review With the expanded roll-out of antiretrovirals for treatment and
prevention of HIV during the last decade, the emergence of HIV drug resistance (HIVDR) …
prevention of HIV during the last decade, the emergence of HIV drug resistance (HIVDR) …
Accumulation of HIV-1 drug resistance after continued virological failure on first-line ART in adults and children in sub-Saharan Africa
TS Boender, CM Kityo, RS Boerma… - Journal of …, 2016 - academic.oup.com
Objectives Limited availability of viral load (VL) monitoring in HIV treatment programmes in
sub-Saharan Africa can delay switching to second-line ART, leading to the accumulation of …
sub-Saharan Africa can delay switching to second-line ART, leading to the accumulation of …
The urgent need for more potent antiretroviral therapy in low-income countries to achieve UNAIDS 90-90-90 and complete eradication of AIDS by 2030
E Ndashimye, EJ Arts - Infectious Diseases of Poverty, 2019 - mednexus.org
Background: Over 90% of Human Immunodeficiency Virus (HIV) infected individuals will be
on treatment by 2020under UNAIDS 90-90-90 global targets. Under World Health …
on treatment by 2020under UNAIDS 90-90-90 global targets. Under World Health …
Challenges faced by caregivers of virally non-suppressed children on the intensive adherence counselling program in Uganda: a qualitative study
E Nasuuna, J Kigozi, PA Muwanguzi, J Babirye… - BMC health services …, 2019 - Springer
Background Of the estimated 130,000 children living with HIV in Uganda, 47% are receiving
ART. Only 39.3% have suppressed HIV-1 viral load to levels below 50 copies per ml …
ART. Only 39.3% have suppressed HIV-1 viral load to levels below 50 copies per ml …
Magnitude and predictors of HIV-Drug resistance in Africa: A protocol for systematic review and meta-analysis
M Melku, HA Gesesew, PR Ward - Plos one, 2022 - journals.plos.org
Introduction Human Immunodeficiency Virus (HIV) is continued to be a major public health
problem in low-income countries and more importantly in Africa. For the last decade, access …
problem in low-income countries and more importantly in Africa. For the last decade, access …
Pretreatment HIV drug resistance results in virological failure and accumulation of additional resistance mutations in Ugandan children
C Kityo, RS Boerma, KCE Sigaloff… - Journal of …, 2017 - academic.oup.com
Background Pretreatment HIV drug resistance (PDR) can impair virological response to
ART, jeopardizing effective treatment for children. Methods Children aged≤ 12 years …
ART, jeopardizing effective treatment for children. Methods Children aged≤ 12 years …
Prevalence of pre-antiretroviral-treatment drug resistance by gender, age, and other factors in HIV-infected individuals initiating therapy in Kenya, 2013–2014
RA Silverman, IA Beck, C Kiptinness… - The Journal of …, 2017 - academic.oup.com
Background Pre-antiretroviral-treatment drug resistance (PDR) is a predictor of human
immunodeficiency virus (HIV) treatment failure. We determined PDR prevalence and …
immunodeficiency virus (HIV) treatment failure. We determined PDR prevalence and …
Primary resistance against integrase strand transfer inhibitors in integrase strand transfer inhibitor-naive patients failing first-and second-line ART in Tanzania
S Henerico, E Lyimo, AN Makubi… - Journal of …, 2022 - academic.oup.com
Abstract Introduction Sub-Saharan African countries are introducing integrase strand
transfer inhibitors (INSTIs) in their ART programmes as the preferred first-line regimen, and …
transfer inhibitors (INSTIs) in their ART programmes as the preferred first-line regimen, and …
Prevalence of antiretroviral therapy treatment failure among HIV-infected pregnant women at first antenatal care: PMTCT Option B+ in Malawi
MB Chagomerana, WC Miller, JH Tang, IF Hoffman… - PLoS …, 2018 - journals.plos.org
Background In Malawi's PMTCT Option B+ program, HIV-infected pregnant women who are
already receiving ART are continued on their current therapy regimen without testing for …
already receiving ART are continued on their current therapy regimen without testing for …
HIV drug resistance in infants increases with changing prevention of mother-to-child transmission regimens
LK Poppe, C Chunda-Liyoka, EH Kwon, C Gondwe… - Aids, 2017 - journals.lww.com
Objectives: The objectives of this study were to determine HIV drug resistance (HIVDR)
prevalence in Zambian infants upon diagnosis, and to determine how changing prevention …
prevalence in Zambian infants upon diagnosis, and to determine how changing prevention …