Novel heart failure biomarkers: why do we fail to exploit their potential?

A Piek, W Du, RA de Boer… - Critical reviews in clinical …, 2018 - Taylor & Francis
Plasma biomarkers are useful tools in the diagnosis and prognosis of heart failure (HF). In
the last decade, numerous studies have aimed to identify novel HF biomarkers that would …

The performance of HE4 alone and in combination with CA125 for the detection of ovarian cancer in an enriched primary care population

CE Barr, G Funston, D Jeevan, S Sundar, LTA Mounce… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer is the most common cause of death from gynaecological
cancer in the UK. Survival is better when the disease is diagnosed early. However …

Recent advances in surface plasmon resonance for the detection of ovarian cancer biomarkers: a thorough review

SV Shahbazlou, S Vandghanooni, B Dabirmanesh… - Microchimica Acta, 2024 - Springer
Early detection of ovarian cancer (OC) is crucial for effective management and treatment, as
well as reducing mortality rates. However, the current diagnostic methods for OC are time …

Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast

RM Karvas, S McInturf, J Zhou, T Ezashi… - Molecular human …, 2020 - academic.oup.com
Human placental development during early pregnancy is poorly understood. Many
conceptuses are lost at this stage. It is thought that preeclampsia, intrauterine growth …

[HTML][HTML] MicroRNA-149 sensitizes colorectal cancer to radiotherapy by downregulating human epididymis protein 4

LP Shi, HL Guo, YB Su, ZH Zheng, JR Liu… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Abstract Human epididymis protein 4 (HE4) was significantly up-regulated in colorectal
cancer (CRC), while the potential relevance to radiation resistance of this phenomenon is …

[HTML][HTML] Optimizing screening for colorectal cancer: an algorithm combining fecal immunochemical test, blood-based cancer-associated proteins and demographics to …

MM Petersen, J Kleif, LN Jørgensen, JW Hendel… - Clinical colorectal …, 2023 - Elsevier
Abstract Background Fecal Immunochemical Test (FIT) is widely used in population-based
screening for colorectal cancer (CRC). This had led to major challenges regarding …

Diagnostic value of combinatorial markers in colorectal carcinoma

V Voronova, P Glybochko, A Svistunov, V Fomin… - Frontiers in …, 2020 - frontiersin.org
Objectives: Blood-based tests have been shown to be an effective strategy for colorectal
cancer (CRC) detection in screening programs. This study was aimed to test the …

Human epididymis protein 4 (HE4) protects against cystic pulmonary fibrosis associated-inflammation through inhibition of NF-κB and MAPK singnaling

J Wang, H Zhao, F Xu, P Zhang, Y Zheng, N Jia - Genes & genomics, 2019 - Springer
Background Cystic pulmonary fibrosis (CF) affects mostly the lung of the newborns. Chronic
infection and inflammation become the major causes of morbidity and mortality in CF …

High levels of human epididymis protein 4 mRNA and protein expression are associated with chemoresistance and a poor prognosis in pancreatic cancer

R Ohkuma, E Yada, S Ishikawa… - International …, 2020 - spandidos-publications.com
Pancreatic cancer is associated with an exceedingly poor prognosis, warranting the
development of novel therapeutic strategies and discovery of prognostic predictors. Given …

[PDF][PDF] Correlation between serum and tissue markers in breast cancer Iraqi patients

AM Hussain, AH Ali, HL Mohammed - Baghdad Science Journal, 2022 - iasj.net
Breast cancer is the most prevalent malignancy among women worldwide, in Iraq it ranks
the first among the population and the leading cause of cancer related female mortality. This …