Navigating financial toxicity in patients with cancer: a multidisciplinary management approach

GL Smith, MP Banegas, C Acquati… - CA: a cancer journal …, 2022 - Wiley Online Library
Approximately one‐half of individuals with cancer face personal economic burdens
associated with the disease and its treatment, a problem known as financial toxicity (FT). FT …

Properties of FDA-approved small molecule protein kinase inhibitors: A 2020 update

R Roskoski Jr - Pharmacological research, 2020 - Elsevier
Because genetic alterations including mutations, overexpression, translocations, and
dysregulation of protein kinases are involved in the pathogenesis of many illnesses, this …

[HTML][HTML] Factors associated with clinical trials that fail and opportunities for improving the likelihood of success: a review

DB Fogel - Contemporary clinical trials communications, 2018 - Elsevier
Clinical trials are time consuming, expensive, and often burdensome on patients. Clinical
trials can fail for many reasons. This survey reviews many of these reasons and offers …

Properties of FDA-approved small molecule protein kinase inhibitors

R Roskoski Jr - Pharmacological research, 2019 - Elsevier
Because mutations, overexpression, and dysregulation of protein kinases play essential
roles in the pathogenesis of many illnesses, this enzyme family has become one of the most …

The financial burden and distress of patients with cancer: understanding and stepping‐up action on the financial toxicity of cancer treatment

PM Carrera, HM Kantarjian… - CA: a cancer journal for …, 2018 - Wiley Online Library
Abstract “Financial toxicity” has now become a familiar term used in the discussion of cancer
drugs, and it is gaining traction in the literature given the high price of newer classes of …

Financial hardships experienced by cancer survivors: a systematic review

CK Altice, MP Banegas… - Journal of the …, 2017 - academic.oup.com
Background: With rising cancer care costs, including high-priced cancer drugs, financial
hardship is increasingly documented among cancer survivors in the United States; research …

Financial burdens of cancer treatment: a systematic review of risk factors and outcomes

GL Smith, MA Lopez-Olivo, PG Advani, MS Ning… - Journal of the National …, 2019 - jnccn.org
Background: Patients with cancer experience financial toxicity from the costs of treatment, as
well as material and psychologic stress related to this burden. A synthesized understanding …

Measuring financial toxicity as a clinically relevant patient‐reported outcome: the validation of the COmprehensive Score for financial Toxicity (COST)

JA De Souza, BJ Yap, K Wroblewski, V Blinder… - Cancer, 2017 - Wiley Online Library
BACKGROUND Cancer and its treatment lead to increased financial distress for patients. To
the authors' knowledge, to date, no standardized patient‐reported outcome measure has …

Fulvestrant 500 mg versus anastrozole 1 mg for hormone receptor-positive advanced breast cancer (FALCON): an international, randomised, double-blind, phase 3 …

JFR Robertson, IM Bondarenko, E Trishkina, M Dvorkin… - The Lancet, 2016 - thelancet.com
Background Aromatase inhibitors are a standard of care for hormone receptor-positive
locally advanced or metastatic breast cancer. We investigated whether the selective …

[HTML][HTML] Financial insolvency as a risk factor for early mortality among patients with cancer

SD Ramsey, A Bansal, CR Fedorenko… - Journal of clinical …, 2016 - ncbi.nlm.nih.gov
Purpose Patients with cancer are more likely to file for bankruptcy than the general
population, but the impact of severe financial distress on health outcomes among patients …