Purpose To create a radiogenomic map linking computed tomographic (CT) image features
and gene expression profiles generated by RNA sequencing for patients with non–small cell …

LRIG1, leucine-rich repeats and immunoglobulin-like domains protein 1, was discovered
more than 20 years ago and has been shown to be downregulated or lost, and to function as …

The bone morphogenetic protein (BMP) pathway promotes differentiation and induces
apoptosis in normal colorectal epithelial cells. However, its role in colorectal cancer (CRC) is …

Immune checkpoint blockade therapy (ICBT) can unleash T-cell responses against cancer.
However, only a small fraction of patients exhibited responses to ICBT. The role of immune …

Intratumoral hypoxia is a well-known feature of solid cancers and constitutes a major
contributor to cancer metastasis and poor outcomes including melanoma. Leucine-rich …

Background Primary vaginal carcinoma (PVC) is a rare malignancy. Established prognostic
factors include tumour stage and age at diagnosis. The leucine-rich repeats and …

Background Lung squamous cell carcinoma (LUSC) accounts for a significant proportion of
cancer deaths worldwide, and is preceded by the appearance of progressively disorganised …

Background: Accumulating studies have demonstrated that the expression of leucine-rich
repeats and immunoglobulin-like domains protein1 (LRIG1) is associated with various types …

Objective: To assess the clinical significance of leucine-rich repeats and immunoglobulin-
like domains protein 1 (LRIG1) and fascin actin-bundling protein 1 (Fascin-1) expression in …

The bone morphogenetic protein (BMP) pathway promotes differentiation and induces
apoptosis in normal colorectal epithelial cells. However, the effect of the BMP pathway in …