[HTML][HTML] All disease begins in the (leaky) gut: role of zonulin-mediated gut permeability in the pathogenesis of some chronic inflammatory diseases

A Fasano - F1000Research, 2020 - ncbi.nlm.nih.gov
Improved hygiene leading to reduced exposure to microorganisms has been implicated as
one possible cause for the recent “epidemic” of chronic inflammatory diseases (CIDs) in …

The role of intestinal mucosal barrier in autoimmune disease: A potential target

J An, Y Liu, Y Wang, R Fan, X Hu, F Zhang… - Frontiers in …, 2022 - frontiersin.org
Autoimmune diseases are a series of diseases involving multiple tissues and organs,
characterized by the over production of abnormal multiple antibodies. Although most studies …

Intestinal barrier dysfunction, LPS translocation, and disease development

SS Ghosh, J Wang, PJ Yannie… - Journal of the Endocrine …, 2020 - academic.oup.com
The intestinal barrier is complex and consists of multiple layers, and it provides a physical
and functional barrier to the transport of luminal contents to systemic circulation. While the …

Butyrate and the fine-tuning of colonic homeostasis: implication for inflammatory bowel diseases

N Gasaly, MA Hermoso, M Gotteland - International journal of molecular …, 2021 - mdpi.com
This review describes current evidence supporting butyrate impact in the homeostatic
regulation of the digestive ecosystem in health and inflammatory bowel diseases (IBDs) …

Zonulin as a potential therapeutic target in microbiota-gut-brain axis disorders: encouraging results and emerging questions

A Veres-Székely, C Szász, D Pap, B Szebeni… - International journal of …, 2023 - mdpi.com
The relationship between dysbiosis and central nervous diseases has been proved in the
last 10 years. Microbial alterations cause increased intestinal permeability, and the …

Highlighting the relevance of gut microbiota manipulation in inflammatory bowel disease

FM Pavel, CM Vesa, G Gheorghe, CC Diaconu… - Diagnostics, 2021 - mdpi.com
Two different conditions are included in inflammatory bowel disease (IBD), Crohn's disease
(CD) and ulcerative colitis (UC), being distinguished by chronic recurrence of gut …

Gut microbial metabolite-mediated regulation of the intestinal barrier in the pathogenesis of inflammatory bowel disease

N Iyer, SC Corr - Nutrients, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disease. The disease has a
multifactorial aetiology, involving genetic, microbial as well as environmental factors. The …

Current evidence on the efficacy of gluten-free diets in multiple sclerosis, psoriasis, type 1 diabetes and autoimmune thyroid diseases

M Passali, K Josefsen, JL Frederiksen, JC Antvorskov - Nutrients, 2020 - mdpi.com
In this review, we summarize the clinical data addressing a potential role for gluten in
multiple sclerosis (MS), psoriasis, type 1 diabetes (T1D) and autoimmune thyroid diseases …

Gut microbiota parameters potentially useful in clinical perspective

F Di Pierro - Microorganisms, 2021 - mdpi.com
Interest in gut microbiota analyses is at an all-time high. Gut microbiota is thought to relate to
an increasing range of diseases of interest to physicians and nutritionists. Overweight …

Coumarin derivatives in inflammatory bowel disease

LC Di Stasi - Molecules, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a non-communicable disease characterized by a
chronic inflammatory process of the gut and categorized into Crohn's disease and ulcerative …