Poisoning from pesticides is a global public health problem and accounts for nearly 300,000
deaths worldwide every year. Exposure to pesticides is inevitable; there are different modes …

Physical plasmas generate unique mixes of reactive oxygen and nitrogen species (RONS or
ROS). Only a bit more than a decade ago, these plasmas, operating at body temperature …

NF-κB proteins are a family of transcription factors that are of central importance in
inflammation and immunity. NF-κB also plays important roles in other processes, including …

Reactive oxygen species (ROS) are highly reactive molecules, mainly generated inside
mitochondria that can oxidize DNA, proteins, and lipids. At physiological levels, ROS …

A pivotal role for excitotoxicity in neurodegenerative diseases is gaining increasingly more
acceptance, but the underlying mechanisms through which it participates in …

The objective of this paper is to present a short review of the state of knowledge regarding
oxidative stress and its role in toxicity of organophosphate insecticides. The information has …

Necrosis plays an important role in multiple physiological and pathological processes.
Recently, a relatively new form of necrosis has been characterized as “necroptosis” …

Zinc (Zn) is an essential element that regulates not only cellular immunity but also
antioxidant and anti-inflammatory agents. The present study investigated the effect of Zn …

Gentamicin is an aminoglycoside antibiotic widely used against infections by Gram-negative
microorganisms. Nephrotoxicity is the main limitation to its therapeutic efficacy. Gentamicin …

In the first part, the following mechanisms involved in different forms of cell death are
considered, with a view to identifying potential therapeutic targets: tumour necrosis factor …