[HTML][HTML] The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases

A DeMaio, S Mehrotra, K Sambamurti… - Journal of …, 2022 - Springer
The adaptive immune system and associated inflammation are vital in surveillance and host
protection against internal and external threats, but can secondarily damage host tissues …

[HTML][HTML] Systematic review of safety and efficacy of rituximab in treating immune-mediated disorders

C Kaegi, B Wuest, J Schreiner, UC Steiner… - Frontiers in …, 2019 - frontiersin.org
Background: During the past years biologic agents (also termed biologicals or biologics)
have become a crucial treatment option in immunological diseases. Numerous articles have …

Behcet's disease: A comprehensive review with a focus on epidemiology, etiology and clinical features, and management of mucocutaneous lesions

E Alpsoy - The Journal of dermatology, 2016 - Wiley Online Library
Behçet's disease (BD) is a chronic, relapsing, inflammatory multisystem disease of unknown
etiology. Oral ulcers, genital ulcers, cutaneous lesions, and ocular and articular involvement …

Understanding uveitis: the impact of research on visual outcomes

MD de Smet, SRJ Taylor, B Bodaghi… - Progress in retinal and …, 2011 - Elsevier
The term uveitis encompasses a very diverse group of inflammatory ocular diseases that
cause a significant burden of legal and economic blindness. Indeed, the socioeconomic …

[HTML][HTML] Guidance on noncorticosteroid systemic immunomodulatory therapy in noninfectious uveitis: fundamentals of care for uveitis (FOCUS) initiative

AD Dick, JT Rosenbaum, HA Al-Dhibi, R Belfort Jr… - Ophthalmology, 2018 - Elsevier
Topic An international, expert-led consensus initiative to develop systematic, evidence-
based recommendations for the treatment of noninfectious uveitis in the era of biologics …

[HTML][HTML] An update on long-acting therapies in chronic sight-threatening eye diseases of the posterior segment: AMD, DMO, RVO, uveitis and glaucoma

F Ghanchi, R Bourne, SM Downes, R Gale, C Rennie… - Eye, 2022 - nature.com
In the real-world setting, there is suboptimal compliance with treatments that require frequent
administration and assessment visits. This undertreatment frequently has negative …

Behçet disease: new aspects

I Bulur, M Onder - Clinics in dermatology, 2017 - Elsevier
Behçet disease is currently considered an “autoinflammatory disease” triggered by infection
and environmental factors in genetically predisposed individuals. Although the disease is …

Update on the use of systemic biologic agents in the treatment of noninfectious uveitis

S Pasadhika, JT Rosenbaum - Biologics: Targets and Therapy, 2014 - Taylor & Francis
Uveitis is one of the leading causes of blindness worldwide. Noninfectious uveitis may be
associated with other systemic conditions, such as human leukocyte antigen B27-related …

[HTML][HTML] Behcet's disease

JR Nair, RJ Moots - Clinical medicine, 2017 - Elsevier
Behçet's disease (BD) is a chronic relapsing and remitting vasculitis of unknown aetiology. It
has the capacity to affect almost all organ systems because of its potential to involve both …

Management of major organ involvement of Behçet's syndrome: a systematic review for update of the EULAR recommendations

Y Ozguler, P Leccese, R Christensen… - …, 2018 - academic.oup.com
Objective To assess the efficacy and safety of treatment modalities for major organ
involvement of Behçet's syndrome (BS), in order to inform the update of the EULAR …