Type 2 diabetes is a serious and common chronic disease resulting from a complex
inheritance-environment interaction along with other risk factors such as obesity and …

Metabolic diseases, such as obesity, metabolic syndrome (MetS) and type 2 diabetes (T2D),
are now a widespread pandemic in the developed world. These pathologies show sex …

Obesity and diabetes are associated with excess caloric intake and reduced energy
expenditure resulting in a negative energy balance. The incidence of diabetes has reached …

Therapeutic targeting of the processes that regulate histone modification is a growing area
of scientific exploration. Although most interest has concentrated on the various families of …

When humans eat more and exercise less, they tend to become obese and unhealthy. The
molecular pathways that link obesity to serious diseases like Type 2 diabetes and …

Diabetes mellitus represents a growing concern, both for public economy and global health.
In fact, it can lead to insidious macrovascular and microvascular complications, impacting …

The effects of global warming are not limited to rising global temperatures and have set in
motion a complex chain of events contributing to climate change. A consequence of global …

Given large sample sizes, whole genome screens are now able to identify even quite
modest contributions of common human genetic variation to disease. These approaches …

There is a strong relationship between metabolism and immunity, which can become
deleterious under conditions of metabolic stress. Obesity, considered a chronic inflammatory …

The chronic low-grade inflammation of adipose tissues, primarily mediated by adipose
tissue macrophages (ATMs), is the key pathogenic link between obesity and metabolic …