Water dynamics in the hydration shells of biomolecules

D Laage, T Elsaesser, JT Hynes - Chemical Reviews, 2017 - ACS Publications
The structure and function of biomolecules are strongly influenced by their hydration shells.
Structural fluctuations and molecular excitations of hydrating water molecules cover a broad …

Water dynamics in the hydration layer around proteins and micelles

B Bagchi - Chemical Reviews, 2005 - ACS Publications
This review deals with dynamics of water molecules in the hydration layer that surrounds
selfassemblies and proteins in aqueous solutions. This topic has not only seen a vigorous …

Dielectric relaxation and solvation dynamics of water in complex chemical and biological systems

N Nandi, K Bhattacharyya, B Bagchi - Chemical Reviews, 2000 - ACS Publications
Because of its unique properties, water drives many natural and biological processes. While
a detailed understanding of its precise role is still being unravelled, it is clear that the …

Dynamics of water in biological recognition

SK Pal, AH Zewail - Chemical Reviews, 2004 - ACS Publications
Almost all biological macromoleculessproteins (enzymes) and DNAsare inactive in the
absence of water. Hydration of a protein/enzyme is particularly important for the stability of …

Slaving: solvent fluctuations dominate protein dynamics and functions

PW Fenimore, H Frauenfelder… - Proceedings of the …, 2002 - National Acad Sciences
Protein motions are essential for function. Comparing protein processes with the dielectric
fluctuations of the surrounding solvent shows that they fall into two classes: nonslaved and …

A natural product that lowers cholesterol as an antagonist ligand for FXR

NL Urizar, AB Liverman, DNT Dodds, FV Silva… - Science, 2002 - science.org
Extracts of the resin of the guggul tree (Commiphora mukul) lower LDL (low-density
lipoprotein) cholesterol levels in humans. The plant sterol guggulsterone [4, 17 (20) …

Biological water at the protein surface: dynamical solvation probed directly with femtosecond resolution

SK Pal, J Peon, AH Zewail - Proceedings of the National …, 2002 - National Acad Sciences
Biological water at the interface of proteins is critical to their equilibrium structures and
enzyme function and to phenomena such as molecular recognition and protein–protein …

[图书][B] Modern optical spectroscopy

WW Parson - 2007 - Springer
2 1 Introduction the most salient points are just that a molecule can exist in a variety of states
depending on how its electrons are distributed among a set of molecular orbitals, and that …

Biological water: femtosecond dynamics of macromolecular hydration

SK Pal, J Peon, B Bagchi… - The Journal of Physical …, 2002 - ACS Publications
The unique features of a macromolecule and water as a solvent make the issue of solvation
unconventional, with questions about the static versus dynamic nature of hydration and the …

On the mechanism of light harvesting in photosynthetic purple bacteria: B800 to B850 energy transfer

GD Scholes, GR Fleming - The Journal of Physical Chemistry B, 2000 - ACS Publications
The rate of energy transfer from B800 to B850 in the peripheral light harvesting complex LH2
is modeled in detail. A method for determining ensemble average energy transfer rates in …