Innate lymphoid cells (ILCs) are enriched at barrier surfaces of the mammalian body where
they rapidly respond to host, microbial or environmental stimuli to promote immunity or …

Dendritic cells, macrophages and B cells are regarded as the classical antigen-presenting
cells of the immune system. However, in recent years, there has been a rapid increase in the …

Microbial colonization of the mammalian intestine elicits inflammatory or tolerogenic T cell
responses, but the mechanisms controlling these distinct outcomes remain poorly …

Inflammatory CD4+ T cell responses to self or commensal bacteria underlie the
pathogenesis of autoimmunity and inflammatory bowel disease (IBD), respectively. Although …

Innate immunity is a rapidly evolving field with novel cell types and molecular pathways
being discovered and paradigms changing continuously. Innate and adaptive immune …

Innate lymphoid cells (ILCs) are newly identified members of the lymphoid lineage that have
emerging roles in mediating immune responses and in regulating tissue homeostasis and …

Group 3 innate lymphoid cells (ILC 3), defined by expression of the transcription factor
retinoid‐related orphan receptor γt, play key roles in the regulation of inflammation and …

Innate lymphocytes—including natural killer cells and the recently discovered innate
lymphoid cells—have crucial roles during infection, tissue injury and inflammation. Innate …

Presentation of peptide: MHCII by RORγ-expressing group 3 innate lymphoid cells (ILC3s),
which are enriched within gut tissue, is required for control of CD4 T-cell responses to …

Immunologic memory is the adaptive immune system's powerful ability to remember a
previous antigen encounter and react with accelerated vigor upon antigen re-exposure. It …