NKG2D is an activating receptor expressed by all NK cells and subsets of T cells. It serves
as a major recognition receptor for detection and elimination of transformed and infected …

The activating receptor NKG2D is peculiar in its capability to bind to numerous and highly
diversified MHC class I-like self-molecules. These ligands are poorly expressed on normal …

The activating receptor NKG2D (natural-killer group 2, member D) and its ligands play an
important role in the NK, γδ+ and CD8+ T-cell-mediated immune response to tumors …

The development of senescence in tissues of different organs and in the immune system are
usually investigated independently of each other although during ageing, senescence in …

Recent evidence indicates that natural killer (NK) cells can negatively regulate T-cell
responses, but the mechanisms behind this phenomenon as a consequence of NK–T-cell …

Stimulatory immune receptor NKG2D binds diverse ligands to elicit differential anti‐tumor
and anti‐virus immune responses. Two conflicting degeneracy recognition models based on …

As the thymus involutes during aging, the T‐cell pool has to be maintained by the periodic
expansion of preexisting T cells during adulthood. A conundrum is that repeated episodes of …

Background Patients with relapsed/refractory acute myeloid leukaemia (AML) with FMS-like
tyrosine kinase 3-internal tandem duplication (FLT3-ITD) have limited treatment options and …

NKG2D and DNAM-1 are two activating receptors, present on the surface of NK cells and
other cells of the immune system. Their ligands–MICA, MICB, ULBP1-6 for NKG2D …

Mammalian pregnancy is an intriguing immunological phenomenon where the
semiallogeneic fetus is not rejected. Tolerance toward the fetus involves a number of …