Selenophosphate synthetases use selenium and ATP to synthesize selenophosphate. This
is required for biological utilization of selenium, most notably for the synthesis of the non …

Selenium (Se) is an essential trace element for several organisms and is mostly present in
proteins as l-selenocysteine (Sec or U). Sec is synthesized on its l-seryl–tRNA Sec to …

Selenium (Se) is an essential trace element used for biosynthesis of selenoproteins and is
acquired either through diet or cellular recycling mechanisms. Selenocysteine lyase (Scly) is …

The diphosphoinositol polyphosphates (PP-IPs) are a central group of eukaryotic
messengers. They regulate numerous processes, including cellular energy homeostasis …

The existence and treatment of rectal cancer are important for the function of defecation and
the quality of life. However, the precise mechanisms of rectal carcinogenesis remain …

Selenophosphate synthetase (SEPHS) was originally discovered in prokaryotes as an
enzyme that catalyzes selenophosphate synthesis using inorganic selenium and ATP as …

Abstract Selenophosphate synthetase 2 (SEPHS2) synthesizes selenide and ATP into
selenophosphate, the selenium donor for selenocysteine (Sec), which is cotranslationally …

Selenophosphate synthetase (SEPHS) synthesizes selenophosphate, the active selenium
donor, using ATP and selenide as substrates. SEPHS was initially identified and isolated …

Selenophosphate synthetase (SPS) catalyzes the synthesis of selenophosphate, the
selenium donor for the biosynthesis of selenocysteine and 2-selenouridine residues in …

In mammalian cells, the incorporation of the 21st amino acid, selenocysteine, into proteins is
guided by the Sec machinery. The function of this protein complex requires several protein …