Fungal response to any stress is intricate, specific, and multilayered, though it employs only
a few evolutionarily conserved regulators. This comes with the assumption that one …

Multidrug resistance (MDR) can be a serious complication for the treatment of cancer as well
as for microbial and parasitic infections. Dysregulated overexpression of several members of …

ABSTRACT ATP-binding cassette (ABC) transporters represent one of the largest protein
superfamilies. Functionally diverse, ABC transporters have been implicated in many aspects …

The ATP binding cassette (ABC) transporters, first discovered as high-affinity nutrient
importers in bacteria, rose to prominence when their ability to confer multidrug resistance …

Abstract The antifungal agent 5-fluorocytosine (5-FC) is used for the treatment of several
mycoses, but is unsuitable for monotherapy due to the rapid development of resistance …

Fungal infections are a serious global concern because of their ability to spread and
colonize host tissues in immunocompromised individuals. Such infections have been …

This review attempts to frame the issues around antifungal drug resistance. From its
epidemiology, mechanisms, measurements, and clinical significance, invasive fungal …

Background: Cross-resistance to medical azoles by exposure to azole pesticides is well
documented for Aspergillus family fungi but is poorly evaluated for other environmental …

Antifungal susceptibility testing (AST) has come to establish itself as a mandatory routine in
clinical practice. At the same time, the mycological diagnosis seems to have headed in the …

The regulation of gene expression in response to increased levels of reactive oxygen
species (ROS) is a ubiquitous response in aerobic organisms. However, different organisms …