Role of dendritic cells in the host response to biomaterials and their signaling pathways
F Zhu, Y Tong, Z Sheng, Y Yao - Acta biomaterialia, 2019 - Elsevier
Strategies to enhance, inhibit, or qualitatively modulate immune responses are important for
diverse biomedical applications such as vaccine adjuvant, drug delivery, immunotherapy …
diverse biomedical applications such as vaccine adjuvant, drug delivery, immunotherapy …
Drebrin controls scar formation and astrocyte reactivity upon traumatic brain injury by regulating membrane trafficking
J Schiweck, K Murk, J Ledderose… - Nature …, 2021 - nature.com
The brain of mammals lacks a significant ability to regenerate neurons and is thus
particularly vulnerable. To protect the brain from injury and disease, damage control by …
particularly vulnerable. To protect the brain from injury and disease, damage control by …
Amlexanox attenuates experimental autoimmune encephalomyelitis by inhibiting dendritic cell maturation and reprogramming effector and regulatory T cell responses
MY Quan, XJ Song, HJ Liu, XH Deng, HQ Hou… - Journal of …, 2019 - Springer
Abstract Background Amlexanox (ALX), a TBK1 inhibitor, can modulate immune responses
and has anti-inflammatory properties. To investigate its role in regulating the progression of …
and has anti-inflammatory properties. To investigate its role in regulating the progression of …
[HTML][HTML] Ginsenoside Rg5 promotes wound healing in diabetes by reducing the negative regulation of SLC7A11 on the efferocytosis of dendritic cells
W Xia, Z Zhu, S Xiang, Y Yang - Journal of Ginseng Research, 2023 - Elsevier
Background: ginsenoside Rg5 is a rare ginsenoside with known hypoglycemic effects in
diabetic mice. This study aimed to explore the effects of ginsenoside Rg5 on skin wound …
diabetic mice. This study aimed to explore the effects of ginsenoside Rg5 on skin wound …
Tropomodulin1 expression increases upon maturation in dendritic cells and promotes their maturation and immune functions
X Liu, X Xia, X Wang, J Zhou, LA Sung, J Long… - Frontiers in …, 2021 - frontiersin.org
Dendritic cells (DCs) are the most potent antigen-presenting cells. Upon maturation, DCs
express costimulatory molecules and migrate to the lymph nodes to present antigens to T …
express costimulatory molecules and migrate to the lymph nodes to present antigens to T …
Single-nuclei transcriptome analysis of channel catfish spleen provides insight into the immunome of an aquaculture-relevant species
JE Aldersey, MD Lange, BH Beck, JW Abernathy - Plos one, 2024 - journals.plos.org
The catfish industry is the largest sector of US aquaculture production. Given its role in food
production, the catfish immune response to industry-relevant pathogens has been …
production, the catfish immune response to industry-relevant pathogens has been …
Pancreatic islets seeded in a novel bioscaffold forms an organoid to rescue insulin production and reverse hyperglycemia in models of type 1 diabetes
DM Elizondo, NZD Brandy, RLL da Silva… - Scientific reports, 2020 - nature.com
Therapeutic approaches to combat type 1 diabetes (T1D) include donor pancreas
transplantation, exogenous insulin administration and immunosuppressive therapies …
transplantation, exogenous insulin administration and immunosuppressive therapies …
Clinical Implications and Molecular Characterization of Drebrin-Positive, Tumor-Infiltrating Exhausted T Cells in Lung Cancer
K Imamura, Y Tomita, R Sato, T Ikeda, S Iyama… - International Journal of …, 2022 - mdpi.com
T cells express an actin-binding protein, drebrin, which is recruited to the contact site
between the T cells and antigen-presenting cells during the formation of immunological …
between the T cells and antigen-presenting cells during the formation of immunological …
Relationship Among the Biophysical Characteristics, Cytoskeletal Structure, and Functions of Dendritic Cells at Different Stages of Differentiation
J Long, X Xu, Y Wang, S Long, H Xiong… - Dendritic Cells …, 2024 - Springer
Dendritic cells (DCs) are the most powerful antigen-presenting cells and play key roles in
the initiation and amplification of innate and adaptive immune responses. Both DCs and …
the initiation and amplification of innate and adaptive immune responses. Both DCs and …
Drebrin mediates scar formation and astrocyte reactivity during brain injury by inducing RAB8 tubular endosomes
J Schiweck, K Murk, J Ledderose… - bioRxiv, 2020 - biorxiv.org
The brain of mammals lacks a significant ability to regenerate neurons and is thus
particularly vulnerable. To protect the brain from injury and disease, damage control by …
particularly vulnerable. To protect the brain from injury and disease, damage control by …