Animal models of chemotherapy-induced cognitive decline in preclinical drug development
Rationale Chemotherapy-induced cognitive impairment (CICI), chemobrain, and chemofog
are the common terms for mental dysfunction in a cancer patient/survivor under the influence …
are the common terms for mental dysfunction in a cancer patient/survivor under the influence …
[HTML][HTML] Artificial and natural interventions for chemotherapy-and/or radiotherapy-induced cognitive impairment: A systematic review of animal studies
LE Kuil, T Varkevisser, MH Huisman, M Jansen… - Neuroscience & …, 2024 - Elsevier
Background Cancer survivors frequently experience cognitive impairments. This systematic
review assessed animal literature to identify artificial (pharmaceutical) or natural …
review assessed animal literature to identify artificial (pharmaceutical) or natural …
Neuroprotective potential of berberine against doxorubicin-induced toxicity in rat's brain
G Ibrahim Fouad, KA Ahmed - Neurochemical Research, 2021 - Springer
Chemotherapy-associated neurotoxicity is one of the principal side-effects for doxorubicin
(DOX)-treated cancer patients. Despite its poor-penetration across the blood–brain barrier …
(DOX)-treated cancer patients. Despite its poor-penetration across the blood–brain barrier …
Alpha-lipoic acid ameliorates doxorubicin-induced cognitive impairments by modulating neuroinflammation and oxidative stress via NRF-2/HO-1 signaling pathway in …
Chemotherapy-induced cognitive impairment (CICI) is a common complication associated
with the use of chemotherapeutics. Doxorubicin (DOX) is a reactive oxygen species (ROS) …
with the use of chemotherapeutics. Doxorubicin (DOX) is a reactive oxygen species (ROS) …
Cannabinoid drugs-related neuroprotection as a potential therapeutic tool against chemotherapy-induced cognitive impairment
In recent years, and particularly associated with the increase of cancer patients' life
expectancy, the occurrence of cancer treatment sequelae, including cognitive impairments …
expectancy, the occurrence of cancer treatment sequelae, including cognitive impairments …
[HTML][HTML] Chemobrain as a product of growing success in chemotherapy-focus on glia as both a victim and a cure
P Walczak, M Janowski - Neuropsychiatry, 2019 - ncbi.nlm.nih.gov
Chemotherapy-induced cognitive impairment or chemobrain is a frequent consequence of
cancer treatment with many psychiatric features. Ironically, the increasing efficacy of …
cancer treatment with many psychiatric features. Ironically, the increasing efficacy of …
[HTML][HTML] The effectiveness of anti-inflammatory agents in reducing chemotherapy-induced cognitive impairment in preclinical models–A systematic review
OJ Haller, I Semendric, RP George… - Neuroscience & …, 2023 - Elsevier
Chemotherapy-induced cognitive impairment (CICI) is a debilitating condition resulting from
chemotherapy administration for cancer treatment. CICI is characterised by various cognitive …
chemotherapy administration for cancer treatment. CICI is characterised by various cognitive …
Microarray expression profiles of lncRNAs and mRNAs in postoperative cognitive dysfunction
Y Zhang, YX Liu, QX Xiao, Q Liu, R Deng… - Frontiers in …, 2018 - frontiersin.org
Postoperative cognitive dysfunction (POCD) is serious disorder in the central nervous
system common in aged patients after anesthesia. Although its clinical symptoms are well …
system common in aged patients after anesthesia. Although its clinical symptoms are well …
Cannabinoid drugs against chemotherapy-induced adverse effects: focus on nausea/vomiting, peripheral neuropathy and chemofog in animal models
A Bagues, Y López-Tofiño… - Behavioural …, 2022 - journals.lww.com
Although new drugs are being developed for cancer treatment, classical chemotherapeutic
agents are still front-line therapies, despite their frequent association with severe side effects …
agents are still front-line therapies, despite their frequent association with severe side effects …
[HTML][HTML] The negative role of histone acetylation in cobalt chloride-induced neurodegenerative damages in SHSY5Y cells
Z Guo, J Tang, J Wang, F Zheng, C Zhang… - Ecotoxicology and …, 2021 - Elsevier
Cobalt has been known for its neurotoxicity in numerous studies. However, the molecular
mechanism underlying cobalt-induced neurotoxicity remains largely unknown. In this study …
mechanism underlying cobalt-induced neurotoxicity remains largely unknown. In this study …