Biological activities of artemisinin derivatives beyond malaria

X Liu, J Cao, G Huang, Q Zhao… - Current Topics in …, 2019 - ingentaconnect.com
Artemisinin is isolated from Artemisia annua L. with peroxide-containing sesquiterpene
lactone structure. Because of its unique structural characteristics and promising anticancer …

The regulatory effects of traditional Chinese medicine on ferroptosis

Q Gao, X Yin, F Zhang, YZ Zhu… - Oxidative Medicine and …, 2022 - Wiley Online Library
Traditional Chinese medicine (TCM) has significantly contributed to protecting human health
and promoting the progress of world civilization. A total of 2,711 TCMs are included in the …

Effectiveness and safety of artesunate–amodiaquine versus artemether–lumefantrine for home-based treatment of uncomplicated Plasmodium falciparum malaria …

PTN Niba, AM Nji, IM Ali, LF Akam, CH Dongmo… - BMC Infectious …, 2022 - Springer
Background Many studies have reported high efficacy and safety of artesunate-amodiaquine
(AS-AQ) and artemether-lumefantrine (AL) when administered under direct observation in …

Adverse Drug Reaction Onsets in Uganda's VigiBase®: Delayed International Visibility, Data Quality and Illustrative Signal Detection Analyses

R Kiguba, HB Ndagije, V Nambasa, SM Bird - Pharmaceutical Medicine, 2018 - Springer
Introduction Developing countries can improve their pharmacovigilance systems by
analysing their own medication safety data. Objective The aims of this study were to …

Mapping the Pharmacogenetic Landscape in a Ugandan Population: Implications for Personalized Medicine in an Underrepresented Population

SR Samarasinghe, S Lee, M Corpas… - Clinical …, 2024 - Wiley Online Library
Africans are extremely underrepresented in global genomic research. African populations
face high burdens of communicable and non‐communicable diseases and experience …

Variation of adverse drug events in different settings in Africa: a systematic review

L Nyame, Y Hu, H Xue, EDK Fiagbey, X Li… - European Journal of …, 2024 - Springer
Abstract Background Adverse drug events (ADEs) represent challenges affecting Africa's
healthcare systems owing to the increased healthcare expenditure and negative health …

Optimal approach and strategies to strengthen pharmacovigilance in sub-Saharan Africa: a cohort study of patients treated with first-line artemisinin-based …

T Rouamba, P Sondo, K Derra… - Drug Design …, 2020 - Taylor & Francis
Background and purpose Resource-limited countries face challenges in setting up effective
pharmacovigilance systems. This study aimed to monitor the occurrence of adverse events …

Cardiotoxicity and cardioprotection by artesunate in larval zebrafish

C Zheng, L Shan, P Tong, T Efferth - Dose-Response, 2020 - journals.sagepub.com
Although artesunate (ART) is generally accepted as a safe and well-tolerated first-line
treatment of severe malaria, cases of severe side effects and toxicity of this compound are …

The effect of community dialogues and sensitization on patient reporting of adverse events in rural Uganda: Uncontrolled before-after study

HB Ndagije, L Manirakiza, D Kajungu, E Galiwango… - PloS one, 2019 - journals.plos.org
Background Patients experiencing adverse drug events (ADE) in many developing countries
are in the best position to report these events to the authorities but need to be empowered to …

Oral Complications related to tropical infectious Diseases: an introduction and analysis of survey data

Y Shuai, Y Lou, L Zhu, W Chen, T Jiang - BMC Oral Health, 2023 - Springer
Backgrounds The non-indigenous tropical infectious diseases that occur in the non-tropics
arise from personnel communication between locals and visitors. Many of these infectious …