Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis
ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …
The purinergic system as a pharmacological target for the treatment of immune-mediated inflammatory diseases
Immune-mediated inflammatory diseases (IMIDs) encompass a wide range of seemingly
unrelated conditions, such as multiple sclerosis, rheumatoid arthritis, psoriasis, inflammatory …
unrelated conditions, such as multiple sclerosis, rheumatoid arthritis, psoriasis, inflammatory …
The roles of adenosine deaminase in autoimmune diseases
Z Gao, X Wang, H Zhang, F Lin, C Liu, K Dong - Autoimmunity Reviews, 2021 - Elsevier
Autoimmune diseases patients are characterized by the autoimmune disorders, whose
immune system can't distinguish between auto-and foreign-antigens. Thus, Immune …
immune system can't distinguish between auto-and foreign-antigens. Thus, Immune …
Oxidative stress marker aberrations in multiple sclerosis: A meta-analysis study
SY Zhang, LN Gui, YY Liu, S Shi, Y Cheng - Frontiers in neuroscience, 2020 - frontiersin.org
Oxidative stress has been suggested to play a key role in multiple sclerosis (MS), but clinical
data on oxidative stress markers in MS patients were inconsistent. This study sought to …
data on oxidative stress markers in MS patients were inconsistent. This study sought to …
Probiotic supplementation and systemic inflammation in relapsing-remitting multiple sclerosis: A randomized, double-blind, placebo-controlled trial
M Rahimlou, S Nematollahi, D Husain… - Frontiers in …, 2022 - frontiersin.org
Background Multiple sclerosis (MS) is a complex inflammatory disease in which
demyelination occurs in the central nervous system affecting approximately 2.5 million …
demyelination occurs in the central nervous system affecting approximately 2.5 million …
Adenosine deaminase inhibition
Adenosine deaminase is a critical enzyme in purine metabolism that regulates intra and
extracellular adenosine concentrations by converting it to inosine. Adenosine is an important …
extracellular adenosine concentrations by converting it to inosine. Adenosine is an important …
[HTML][HTML] MSRV envelope protein is a potent, endogenous and pathogenic agonist of human toll-like receptor 4: relevance of GNbAC1 in multiple sclerosis treatment
Multiple sclerosis associated retrovirus envelope protein (MSRV-Env) was repeatedly
detected in brain lesions and blood of multiple sclerosis (MS) patients. We performed the …
detected in brain lesions and blood of multiple sclerosis (MS) patients. We performed the …
Epitranscriptomic modifications modulate normal and pathological functions in CNS
RNA is more than just a combination of four genetically encoded nucleobases as it carries
extra information in the form of epitranscriptomic modifications. Diverse chemical groups …
extra information in the form of epitranscriptomic modifications. Diverse chemical groups …
Exploring the role of neurotransmitters in multiple sclerosis: an expanded review
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system (CNS). Although emerging evidence has shown that changes in …
central nervous system (CNS). Although emerging evidence has shown that changes in …
Possible role of butyrylcholinesterase in fat loss and decreases in inflammatory levels in patients with multiple sclerosis after treatment with epigallocatechin gallate …
JE de la Rubia Ortí, JL Platero, IH Yang, JJ Ceron… - Nutrients, 2021 - mdpi.com
(1) Background. Multiple sclerosis (MS) is characterised by the loss of muscle throughout the
course of the disease, which in many cases is accompanied by obesity and related to …
course of the disease, which in many cases is accompanied by obesity and related to …