The genomic basis of parasitism in the Strongyloides clade of nematodes

VL Hunt, IJ Tsai, A Coghlan, AJ Reid, N Holroyd… - Nature …, 2016 - nature.com
Soil-transmitted nematodes, including the Strongyloides genus, cause one of the most
prevalent neglected tropical diseases. Here we compare the genomes of four Strongyloides …

The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus

EM Schwarz, PK Korhonen, BE Campbell, ND Young… - Genome biology, 2013 - Springer
Background The barber's pole worm, Haemonchus contortus, is one of the most
economically important parasites of small ruminants worldwide. Although this parasite can …

Understanding Haemonchus contortus better through genomics and transcriptomics

RB Gasser, EM Schwarz, PK Korhonen… - Advances in …, 2016 - Elsevier
Parasitic roundworms (nematodes) cause substantial mortality and morbidity in animals
globally. The barber's pole worm, Haemonchus contortus, is one of the most economically …

Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor

X Wang, W Li, D Zhao, B Liu, Y Shi, B Chen… - Nature cell …, 2010 - nature.com
During apoptosis, dying cells are swiftly removed by phagocytes. It is not fully understood
how apoptotic cells are recognized by phagocytes. Here we report the identification and …

High throughput LC-MS/MS-based proteomic analysis of excretory-secretory products from short-term in vitro culture of Haemonchus contortus

T Wang, G Ma, CS Ang, PK Korhonen, AV Koehler… - Journal of …, 2019 - Elsevier
Parasitic nematodes of humans, animals and plants have a major, adverse impact on global
health and agricultural production worldwide. To cope with their surrounding environment in …

Proteomic Analysis of Adult Ascaris suum Fluid Compartments and Secretory Products

JF Chehayeb, AP Robertson, RJ Martin… - PLoS neglected …, 2014 - journals.plos.org
Background Strategies employed by parasites to establish infections are poorly understood.
The host-parasite interface is maintained through a molecular dialog that, among other …

Cracking the nodule worm code advances knowledge of parasite biology and biotechnology to tackle major diseases of livestock

R Tyagi, A Joachim, B Ruttkowski, BA Rosa… - Biotechnology …, 2015 - Elsevier
Many infectious diseases caused by eukaryotic pathogens have a devastating, long-term
impact on animal health and welfare. Hundreds of millions of animals are affected by …

Mining nematode protein secretomes to explain lifestyle and host specificity

L Tritten, C Ballesteros, R Beech… - PLoS Neglected …, 2021 - journals.plos.org
Parasitic nematodes are highly successful pathogens, inflicting disease on humans, animals
and plants. Despite great differences in their life cycles, host preference and transmission …

[HTML][HTML] First transcriptomic analysis of the economically important parasitic nematode, Trichostrongylus colubriformis, using a next-generation sequencing approach

C Cantacessi, M Mitreva, BE Campbell, RS Hall… - Infection, Genetics and …, 2010 - Elsevier
Trichostrongylus colubriformis (Strongylida), a small intestinal nematode of small ruminants,
is a major cause of production and economic losses in many countries. The aims of the …

6-OHDA-induced dopaminergic neurodegeneration in Caenorhabditis elegans is promoted by the engulfment pathway and inhibited by the transthyretin-related …

SL Offenburger, XY Ho, T Tachie-Menson… - PLoS …, 2018 - journals.plos.org
Oxidative stress is linked to many pathological conditions including the loss of dopaminergic
neurons in Parkinson's disease. The vast majority of disease cases appear to be caused by …