Embryo implantation in the laboratory: an update on current techniques

S Ojosnegros, A Seriola, AL Godeau… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND The embryo implantation process is crucial for the correct establishment
and progress of pregnancy. During implantation, the blastocyst trophectoderm cells attach to …

Selective progesterone receptor modulators—mechanisms and therapeutic utility

MS Islam, S Afrin, SI Jones, J Segars - Endocrine Reviews, 2020 - academic.oup.com
Selective progesterone receptor modulators (SPRMs) are a new class of compounds
developed to target the progesterone receptor (PR) with a mix of agonist and antagonist …

Modeling embryo-endometrial interface recapitulating human embryo implantation

S Shibata, S Endo, LAE Nagai, E H. Kobayashi… - Science …, 2024 - science.org
The initiation of human pregnancy is marked by the implantation of an embryo into the
uterine environment; however, the underlying mechanisms remain largely elusive. To …

Trophectoderm differentiation to invasive syncytiotrophoblast is promoted by endometrial epithelial cells during human embryo implantation

PT Ruane, T Garner, L Parsons… - Human …, 2022 - academic.oup.com
STUDY QUESTION How does the human embryo breach the endometrial epithelium at
implantation? SUMMARY ANSWER Embryo attachment to the endometrial epithelium …

Emergency Contraception: A Last Chance to Prevent Unintended Pregnancy.

J Trussell, EG Raymond, K Cleland - … Readings in Law & Social Justice, 2014 - ceeol.com
Emergency contraception provides women with a last chance to prevent unintended
pregnancy after sex. In the United States, available options for emergency contraception are …

State of emergency contraception in the US, 2018

KO Haeger, J Lamme, K Cleland - Contraception and reproductive …, 2018 - Springer
Emergency contraception is indicated in instances of unprotected sexual intercourse,
including reproductive coercion, sexual assault, and contraceptive failure. It plays a role in …

Oral emergency contraception with levonorgestrel plus piroxicam: a randomised double-blind placebo-controlled trial

RHW Li, SST Lo, K Gemzell-Danielsson, CHY Fong… - The Lancet, 2023 - thelancet.com
Background Levonorgestrel, a standard drug for emergency contraception (EC), is not
effective if administered post-ovulation. A cyclo-oxygenase inhibitor could contribute …

Molecular mechanisms of membrane interaction at implantation

LM Davidson, K Coward - Birth Defects Research Part C …, 2016 - Wiley Online Library
Successful pregnancy is dependent upon the implantation of a competent embryo into a
receptive endometrium. Despite major advancement in our understanding of reproductive …

Uterine tissue engineering: where we stand and the challenges ahead

GHDR Almeida, RP Iglesia, MS Araujo… - … Engineering Part B …, 2022 - liebertpub.com
Tissue engineering is an innovative approach to develop allogeneic tissues and organs.
The uterus is a very sensitive and complex organ, which requires refined techniques to …

Generation of porcine endometrial organoids and their use as a model for enhancing embryonic attachment and elongation

IM Saadeldin, A Han, S Bang, H Kang, H Kim… - …, 2024 - rep.bioscientifica.com
In brief Porcine endometrial organoids (EOs) were isolated and characterized, revealing
distinctive features such as unique extracellular matrix formation, fusion into uterine bud-like …