Regulation and role of fungal secondary metabolites

J Macheleidt, DJ Mattern, J Fischer… - Annual review of …, 2016 - annualreviews.org
Fungi have the capability to produce a tremendous number of so-called secondary
metabolites, which possess a multitude of functions, eg, communication signals during …

Coordination of secondarymetabolism and development in fungi: the velvet familyof regulatory proteins

Ö Bayram, GH Braus - FEMS microbiology reviews, 2012 - academic.oup.com
Filamentous fungi produce a number of small bioactive molecules as part of their secondary
metabolism ranging from benign antibiotics such as penicillin to threatening mycotoxins …

The Aspergillus nidulans MAPK Module AnSte11-Ste50-Ste7-Fus3 Controls Development and Secondary Metabolism

Ö Bayram, ÖS Bayram, YL Ahmed, J Maruyama… - PLoS …, 2012 - journals.plos.org
The sexual Fus3 MAP kinase module of yeast is highly conserved in eukaryotes and
transmits external signals from the plasma membrane to the nucleus. We show here that the …

Identification and characterization of genes required for cell-to-cell fusion in Neurospora crassa

C Fu, P Iyer, A Herkal, J Abdullah, A Stout… - Eukaryotic cell, 2011 - Am Soc Microbiol
ABSTRACT A screening procedure was used to identify cell fusion (hyphal anastomosis)
mutants in the Neurospora crassa single gene deletion library. Mutants with alterations in 24 …

Protein kinase C in fungi—more than just cell wall integrity

JJ Heinisch, R Rodicio - FEMS Microbiology Reviews, 2018 - academic.oup.com
Human protein kinase C (PKC) isoforms have been implicated in diseases such as
Alzheimer's, diabetes and cancers. In contrast to mammals, which have at least nine genes …

The MpkA MAP kinase module regulates cell wall integrity signaling and pyomelanin formation in Aspergillus fumigatus

V Valiante, R Jain, T Heinekamp… - Fungal Genetics and …, 2009 - Elsevier
Aspergillus fumigatus is the most important air-borne fungal pathogen, causing severe
infections in immunocompromised patients. Mitogen-activated protein kinase (MAPK) …

Genetic networks that govern sexual reproduction in the Pezizomycotina

AM Wilson, PM Wilken, MJ Wingfield… - … and Molecular Biology …, 2021 - Am Soc Microbiol
Sexual development in filamentous fungi is a complex process that relies on the precise
control of and interaction between a variety of genetic networks and pathways. The mating …

The MAPKK FgMkk1 of Fusarium graminearum regulates vegetative differentiation, multiple stress response, and virulence via the cell wall integrity and high …

Y Yun, Z Liu, J Zhang, WB Shim… - Environmental …, 2014 - Wiley Online Library
Mitogen‐activated protein (MAP) kinases play crucial roles in regulating fungal
development, growth and pathogenicity, and in responses to the environment. In this study …

Transcriptome Analysis and Its Application in Identifying Genes Associated with Fruiting Body Development in Basidiomycete Hypsizygus marmoreus

J Zhang, A Ren, H Chen, M Zhao, L Shi, M Chen… - PloS one, 2015 - journals.plos.org
To elucidate the mechanisms of fruit body development in H. marmoreus, a total of
43609521 high-quality RNA-seq reads were obtained from four developmental stages …

The MAP kinase Bbslt2 controls growth, conidiation, cell wall integrity, and virulence in the insect pathogenic fungus Beauveria bassiana

X Luo, NO Keyhani, X Yu, Z He, Z Luo, Y Pei… - Fungal genetics and …, 2012 - Elsevier
Entomopathogenic fungi, such as Beauveria bassiana, are key environmental pathogens of
insects that have been exploited for biological control of insect pests. Mitogen-activated …