Many research questions in fields such as personalized medicine, drug screens or systems
biology depend on obtaining consistent and quantitatively accurate proteomics data from …

Cancer with heavily economic and social burden is the hot point in the field of medical
research. Some remarkable achievements have been made; however, the exact …

Monomethylation of histone H3 at lysine 4 (H3K4me1) and acetylation of histone H3 at
lysine 27 (H3K27ac) are correlated with transcriptionally engaged enhancer elements, but …

Extracellular vesicles (EVs) are a unique mode of intercellular communication capable of
incredible specificity in transmitting signals involved in cellular function, including germ cell …

Targeted proteomics technique has emerged as a powerful protein quantification tool in
systems biology, biomedical research, and increasing for clinical applications. The most …

In the era of quantitative proteomics, where mass spectrometry plays a pivotal role, in
particular associated with the use of data‐independent acquisition, it is time to perform an …

Epigenetics has become a fundamental scientific discipline with various implications for
biology and medicine. Epigenetic marks, mostly DNA methylation and histone post …

Introduction: While selected/multiple-reaction monitoring (SRM or MRM) is considered the
gold standard for quantitative protein measurement, emerging data-independent acquisition …

Histone acetylation is governed by nuclear acetyl-CoA pools generated, in part, from local
acetate by metabolic enzyme acetyl-CoA synthetase 2 (ACSS2). We hypothesize that during …

Heterochromatic DNA domains have important roles in the regulation of gene expression
and maintenance of genome stability by silencing repetitive DNA elements and transposons …