Oxidative stress triggers ferroptosis, a form of cellular necrosis characterized by iron-
dependent lipid peroxidation, and has been implicated in Mycobacterium tuberculosis (Mtb) …

Background/Objectives: Mycobacterium tuberculosis (M. tb) is a pathogen that causes
tuberculosis (TB), an extremely infectious disease which is responsible for millions of deaths …

Glutathione (GSH) is an important intracellular antioxidant responsible for neutralizing
reactive oxygen species (ROS). Our laboratory previously demonstrated that the oral …

Mycobacterium tuberculosis (Mtb), the main pathogen responsible for the high mortality and
morbidity of tuberculosis (TB) worldwide, primarily targets and invades macrophages …

Mycobacterium tuberculosis (M. tb), the causative agent of tuberculosis (TB), is responsible
for causing significant morbidity and mortality, especially among individuals with …

Cellular necrosis during Mycobacterium tuberculosis (Mtb) infection promotes both
immunopathology and bacterial dissemination. Glutathione peroxidase-4 (Gpx4) is an …

Background: Extrapulmonary tuberculosis (EPTB) accounts for a fifth of all Mycobacterium
tuberculosis (M. tb) infections worldwide. The rise of multidrug resistance in M. tb alongside …

Background Latent tuberculosis infection is an asymptomatic infection caused by
Mycobacterium tuberculosis. Previous studies have shown a host-protective role for heme …

Background: The latent TB infection (LTBI) is an asymptomatic infection caused by
Mycobacterium tuberculosis (M. bt). Previous studies have shown a host-protective role for …

Evolution has created a hierarchy of systems for information and energy using different cells
according to messages generated from DNA, RNA, and other sources. Erythrocytes are …