[HTML][HTML] Glucagon-like peptide 1 (GLP-1)

TD Müller, B Finan, SR Bloom, D D'Alessio… - Molecular …, 2019 - Elsevier
Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …

[HTML][HTML] Fermented foods: Harnessing their potential to modulate the microbiota-gut-brain axis for mental health

R Balasubramanian, E Schneider, E Gunnigle… - Neuroscience & …, 2024 - Elsevier
Over the past two decades, whole food supplementation strategies have been leveraged to
target mental health. In addition, there has been increasing attention on the ability of gut …

Central and peripheral GLP-1 systems independently suppress eating

DI Brierley, MK Holt, A Singh, A de Araujo… - Nature …, 2021 - nature.com
The anorexigenic peptide glucagon-like peptide-1 (GLP-1) is secreted from gut
enteroendocrine cells and brain preproglucagon (PPG) neurons, which, respectively, define …

Putting together pieces of the lateral septum: multifaceted functions and its neural pathways

CA Rizzi-Wise, DV Wang - ENeuro, 2021 - eneuro.org
The lateral septum (LS) is implicated as a hub that regulates a variety of affects, such as
reward, feeding, anxiety, fear, sociability, and memory. However, it remains unclear how the …

Brain GLP‐1 and the regulation of food intake: GLP‐1 action in the brain and its implications for GLP‐1 receptor agonists in obesity treatment

S Trapp, DI Brierley - British Journal of Pharmacology, 2022 - Wiley Online Library
This review considers the similarities and differences between the physiological systems
regulated by gut‐derived and neuronally produced glucagon‐like peptide 1 (GLP‐1). It …

Can GLP-1 be a target for reward system related disorders? A qualitative synthesis and systematic review analysis of studies on palatable food, drugs of abuse, and …

CY Eren-Yazicioglu, A Yigit, RE Dogruoz… - Frontiers in Behavioral …, 2021 - frontiersin.org
The role of glucagon-like peptide 1 (GLP-1) in insulin-dependent signaling is well-known;
GLP-1 enhances glucose-dependent insulin secretion and lowers blood glucose in …

[HTML][HTML] The obesity epidemic in the face of homeostatic body weight regulation: What went wrong and how can it be fixed?

HR Berthoud, CD Morrison, H Münzberg - Physiology & behavior, 2020 - Elsevier
Ever since the pioneering discoveries in the mid nineteen hundreds, the hypothalamus was
recognized as a crucial component of the neural system controlling appetite and energy …

Parallel ventral hippocampus-lateral septum pathways differentially regulate approach-avoidance conflict

DCM Yeates, D Leavitt, S Sujanthan, N Khan… - Nature …, 2022 - nature.com
The ability to resolve an approach-avoidance conflict is critical to adaptive behavior. The
ventral CA3 (vCA3) and CA1 (vCA1) subfields of the ventral hippocampus (vHPC) have …

Ghrelin and glucagon-like peptide-1: a gut-brain axis battle for food reward

L Decarie-Spain, SE Kanoski - Nutrients, 2021 - mdpi.com
Eating behaviors are influenced by the reinforcing properties of foods that can favor
decisions driven by reward incentives over metabolic needs. These food reward-motivated …

Gut peptide regulation of food intake–evidence for the modulation of hedonic feeding

ORM Woodward, FM Gribble… - The Journal of …, 2022 - Wiley Online Library
The number of people living with obesity has tripled worldwide since 1975 with serious
implications for public health, as obesity is linked to a significantly higher chance of early …