Novel Para-Aminobenzoic Acid Analogs and Their Potential Therapeutic Applications

F Haroon, U Farwa, M Arif, MA Raza, ZA Sandhu… - Biomedicines, 2023 - mdpi.com
A “building block” is a key component that plays a substantial and critical function in the
pharmaceutical research and development industry. Given its structural versatility and ability …

Reduction of Bacterial Folic Acid Production and Cell Membrane Disruption of Klebsiella pneumoniae by Two Amino Substituted Pyridyl Compounds: An …

JTP Matshwele, M Jongman, TB Demissie… - Chemistry Africa, 2023 - Springer
As bacterial resistance increases, more effective antibiotics are needed, necessitating drug
discovery research. Therefore, in this paper we discuss the potential modes of action of two …

Cobalt pyridyl complexes against drug-resistant bacteria: Synthesis, characterization, antibacterial properties, mode of action, and molecular docking studies

JTP Matshwele, S Odisitse, O Mazimba… - Inorganica Chimica …, 2024 - Elsevier
This study describes the synthesis and characterization of four cobalt complexes using
diverse physicochemical techniques. Notably, the co-grinding method was predominantly …

Antibacterial Activity of Marine Sponge (Stylotella sp.)

NKT Dharmayani, M Ulfa, E Yuanita… - Jurnal Penelitian …, 2023 - jppipa.unram.ac.id
Sponges are marine biota that makes up coral reefs that live on the bottom of the waters and
have an important role in marine ecosystems. Sponges have bioactive components that …

Synthesis, characterization, antibacterial properties, mode of action and molecular docking studies of copper pyridyl complexes against drug-resistant bacteria

JTP Matshwele, S Odisitse, TB Demissie… - Inorganic Chemistry …, 2023 - Elsevier
A series of four new copper complexes containing pyridyl-based ligands of the type [Cu (Cl)
2 (L) 2] were prepared by solid-state methods and evaluated for antibacterial activity. Their …

[HTML][HTML] Nickel mixed ligand complexes against drug resistant bacteria: Synthesis, characterization, antibacterial activities and molecular docking studies

S Odisitse, JTP Matshwele, O Mazimba, TB Demissie… - Results in …, 2023 - Elsevier
Five new nickel complexes of the type NiCl 2 L 2 where (L is 4-picolylchloride (4PY), pyridin-
4-ylmethyl 4-nitrobenzoate (L1), 4-(pyridine-4-ylmethoxy) aniline (L2), pyridin-4-ylmethyl 4 …

[PDF][PDF] Results in Chemistry

Five new nickel complexes of the type NiCl2L2 where (L is 4-picolylchloride (4PY), pyridin-4-
ylmethyl 4-nitrobenzoate (L1), 4-(pyridine-4-ylmethoxy) aniline (L2), pyridin-4-ylmethyl 4 …