Peptide vaccines as therapeutic and prophylactic agents for female-specific cancers: the current landscape
M Lekshmy, CR Dhanya, JSK Smrithi, JA Sindhurani… - Pharmaceuticals, 2023 - mdpi.com
Breast and gynecologic cancers are significant global threats to women's health and those
living with the disease require lifelong physical, financial, and social support from their …
living with the disease require lifelong physical, financial, and social support from their …
In silico formulation of a next-generation multiepitope vaccine for use as a prophylactic candidate against Crimean-Congo hemorrhagic fever
Abstract Background Crimean-Congo hemorrhagic fever (CCHF) is a widespread disease
transmitted to humans and livestock animals through the bite of infected ticks or close …
transmitted to humans and livestock animals through the bite of infected ticks or close …
Epitope screening and vaccine molecule design of PRRSV GP3 and GP5 protein based on immunoinformatics
D Liu, Y Chen - Journal of Cellular and Molecular Medicine, 2024 - Wiley Online Library
Porcine reproductive and respiratory syndrome (PRRS) is a respiratory disease in pigs that
causes severe economic losses. Currently, live PRRSV vaccines are commonly used but fail …
causes severe economic losses. Currently, live PRRSV vaccines are commonly used but fail …
Designing and development of multi-epitope chimeric vaccine against Helicobacter pylori by exploring its entire immunogenic epitopes: an immunoinformatic …
Background Helicobacter pylori is a prominent causative agent of gastric ulceration, gastric
adenocarcinoma and gastric lymphoma and have been categorised as a group 1 …
adenocarcinoma and gastric lymphoma and have been categorised as a group 1 …
A subunit vaccine against pneumonia: targeting Streptococcus pneumoniae and Klebsiella pneumoniae
Community-acquired pneumonia is primarily caused by Streptococcus pneumoniae and
Klebsiella pneumoniae, two pathogens that have high morbidity and mortality rates. This is …
Klebsiella pneumoniae, two pathogens that have high morbidity and mortality rates. This is …
An immunoinformatics study reveals a new BoLA-DR-restricted CD4+ T cell epitopes on the Gag protein of bovine leukemia virus
A Pluta, TM Taxis, F van der Meer, S Shrestha… - Scientific Reports, 2023 - nature.com
Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis (EBL), which
has been reported worldwide. The expression of viral structural proteins: surface …
has been reported worldwide. The expression of viral structural proteins: surface …
Reverse vaccinology approaches to design a potent multiepitope vaccine against the HIV whole genome: immunoinformatic, bioinformatics, and molecular dynamics …
A Hashempour, N Khodadad, S Akbarinia… - BMC infectious …, 2024 - Springer
Substantial advances have been made in the development of promising HIV vaccines to
eliminate HIV-1 infection. For the first time, one hundred of the most submitted HIV subtypes …
eliminate HIV-1 infection. For the first time, one hundred of the most submitted HIV subtypes …
Design of multivalent-epitope vaccine models directed toward the world's population against HIV-Gag polyprotein: Reverse vaccinology and immunoinformatics
Significant progress has been made in HIV-1 research; however, researchers have not yet
achieved the objective of eradicating HIV-1 infection. Accordingly, in this study, eucaryotic …
achieved the objective of eradicating HIV-1 infection. Accordingly, in this study, eucaryotic …
[HTML][HTML] Computational method for designing vaccines applied to virus-like particles (VLPs) as epitope carriers
P Prosper, RR Puertas, DMA Guérin, MM Branda - Vaccine, 2024 - Elsevier
Nonenveloped virus-like particles (VLPs) are self-assembled oligomeric structures
composed of one or more proteins that originate from diverse viruses. Because these VLPs …
composed of one or more proteins that originate from diverse viruses. Because these VLPs …
A novel immunoinformatics approach for developing a poly-epitope vaccine targeting foot and mouth disease virus, exploiting structural VP proteins
Foot and mouth Disease virus (FMDV) belongs to Picornaviridae family and Aphthovirus
genus causing Foot and mouth disease (FMD) in cloven-hoofed animals. FMDV, a prevalent …
genus causing Foot and mouth disease (FMD) in cloven-hoofed animals. FMDV, a prevalent …