Chronic low-grade inflammation in adipose tissue (AT) is a hallmark of obesity and
contributes to various metabolic disorders, such as type 2 diabetes and cardiovascular …

Characterized by a surplus of whole-body adiposity, obesity is strongly associated with the
prognosis of atherosclerosis, a hallmark of coronary artery disease (CAD) and the major …

Research on obesity-and diabetes mellitus (DM)-related carcinogenesis has expanded
exponentially since these two diseases were recognized as important risk factors for …

The human 25-kDa Lipocalin 2 (LCN2) was first identified and purified as a protein that in
part is associated with gelatinase from neutrophils. This protein shows a high degree of …

Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

Mesenchymal stromal cells (MSCs) are a heterogenous cell population found in a wide
range of tissues in the body, known for their nutrient-producing and immunomodulatory …

Bone marrow adipose tissue (BMAT) has been considered for several decades as a silent
bystander that fills empty space left in bone marrow following age-related decrease in …

The growing burden of obesity and osteoporosis is a major public health concern. Emerging
evidence of the role of adipokines on bone metabolism has led to the discovery of novel …

The interplay between adipokines and pancreatic beta cells, often referred to as the adipo-
insular axis, plays a crucial role in regulating metabolic homeostasis. Adipokines are …

Abstract Purpose of Review Obesity is highly prevalent and is associated with bone fragility
and fracture. The changing nutrient availability to bone in obesity is an important facet of …