Epilepsy is a devastating neurological disorder characterized by the repeated occurrence of
epileptic seizures. Epilepsy stands as a global health concern affecting around 70 million …

Potassium channels are widely distributed integral proteins responsible for the effective and
selective transport of K+ ions through the biological membranes. According to the existing …

Mitochondrial potassium channels have been implicated in cytoprotective mechanisms.
Activation of the mitochondrial large-conductance Ca 2+-regulated potassium (mitoBK Ca) …

Background: Quercetin is the main dietary flavonoid with a wide range of pharmacological
activities. However, the poor gastrointestinal absorption and low bioavailability of quercetin …

Possessing unique physical and chemical properties, C 60 fullerenes are arising as a
potential nanotechnological tool that can strongly affect various biological processes …

The activity of mitochondrial large-conductance voltage-and C a 2+-activated K+ channels
(mitoBK) is regulated by a number of biochemical factors, including flavonoids. In particular …

Traditional Chinese medicine (TCM) formulas, including the Er-Long-Zuo-Ci pill, Tong-Qiao-
Er-Long pill, and Er-Long pill, have long been utilized in China for managing age-related …

The largest biomass of channel proteins is located in unicellular organisms and bacteria that
have no organs. However, orchestrated bidirectional ionic currents across the cell …

Quercetin and curcumin are plant polyphenolic antioxidants with proven pharmacological
efficacy. Their use is, however, limited due to low bioavailability and oral administration …

Atualmente o plastificante bisfenol A (BPA) é um dos químicos produzidos em maior volume
mundialmente. O BPA está presente em plásticos policarbonatos e resinas epóxi …