The most widespread intracellular bacteria in the animal kingdom are maternally inherited
endosymbionts of the genus Wolbachia. Their prevalence in arthropods and nematodes …

Wolbachia are successful Gram-negative bacterial endosymbionts, globally infecting a large
fraction of arthropod species and filarial nematodes. Efficient vertical transmission, the …

The radiation-based sterile insect technique (SIT) has successfully suppressed field
populations of several insect pest species, but its effect on mosquito vector control has been …

Animal hosts have initiated myriad symbiotic associations with microorganisms and often
have maintained these symbioses for millions of years, spanning drastic changes in …

Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …

Cytoplasmic incompatibility (CI) is the most common symbiont-induced reproductive
manipulation. Specifically, symbiont-induced sperm modifications cause catastrophic mitotic …

Progress has been made in developing the maternally inherited endosymbiotic bacterium
Wolbachia as a tool for protecting humans from mosquito-borne diseases. In contrast …

Introduced transinfections of the inherited bacteria Wolbachia can inhibit transmission of
viruses by Aedes mosquitoes, and in Ae. aegypti are now being deployed for dengue control …

Mosquito-transmitted diseases account for about 500 000 deaths every year. Blocking these
pathogens in the mosquito vector before they are transmitted to humans is an effective …

Bacterial symbionts, such as Wolbachia species, can manipulate the sexual development
and reproduction of their insect hosts. For example, Wolbachia infection induces male …