The Insula: A Critical Neural Substrate for Drug Seeking under Conflict and Risk
This chapter begins with a summary of the initial findings on the effects of insula lesions on
smoking behavior as well as more recent human‐lesion studies that replicate and extend …
smoking behavior as well as more recent human‐lesion studies that replicate and extend …
[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation
Over the last decade, the understanding of the habenula has rapidly advanced from being
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
The brain disease model of addiction: is it supported by the evidence and has it delivered on its promises?
Summary Since 1997 the US National Institute on Drug Abuse has advocated a brain
disease model of addiction (BDMA). We assess the strength of evidence for the BDMA in …
disease model of addiction (BDMA). We assess the strength of evidence for the BDMA in …
The organization of prefrontal-subthalamic inputs in primates provides an anatomical substrate for both functional specificity and integration: implications for Basal …
WIA Haynes, SN Haber - Journal of Neuroscience, 2013 - Soc Neuroscience
The identification of a hyperdirect cortico-subthalamic nucleus connection highlighted the
important role of the subthalamic nucleus (STN) in regulating behavior. However, this …
important role of the subthalamic nucleus (STN) in regulating behavior. However, this …
Unbalanced neuronal circuits in addiction
Through sequential waves of drug-induced neurochemical stimulation, addiction co-opts the
brain's neuronal circuits that mediate reward, motivation to behavioral inflexibility and a …
brain's neuronal circuits that mediate reward, motivation to behavioral inflexibility and a …
Efficacy of invasive and non-invasive brain modulation interventions for addiction
It is important to find new treatments for addiction due to high relapse rates despite current
interventions and due to expansion of the field with non-substance related addictive …
interventions and due to expansion of the field with non-substance related addictive …
A comprehensive review of emerging trends and innovative therapies in epilepsy management
Epilepsy is a complex neurological disorder affecting millions worldwide, with a substantial
number of patients facing drug-resistant epilepsy. This comprehensive review explores …
number of patients facing drug-resistant epilepsy. This comprehensive review explores …
Translating the habenula—from rodents to humans
The habenula (Hb) is a central structure connecting forebrain to midbrain regions. This
microstructure regulates monoaminergic systems, notably dopamine and serotonin, and …
microstructure regulates monoaminergic systems, notably dopamine and serotonin, and …
Probabilistic conversion of neurosurgical DBS electrode coordinates into MNI space
In neurosurgical literature, findings such as deep brain stimulation (DBS) electrode positions
are conventionally reported in relation to the anterior and posterior commissures of the …
are conventionally reported in relation to the anterior and posterior commissures of the …
Deep brain stimulation of the nucleus accumbens in treatment-resistant alcohol use disorder: a double-blind randomized controlled multi-center trial
P Bach, M Luderer, UJ Müller, M Jakobs… - Translational …, 2023 - nature.com
Abstract Treatment resistance in alcohol use disorders (AUD) is a major problem for affected
individuals and for society. In the search of new treatment options, few case studies using …
individuals and for society. In the search of new treatment options, few case studies using …