Analysis of age-dependent gene-expression in human tissues for studying diabetes comorbidities

PH Guzzi, F Cortese, GC Mannino, E Pedace… - Scientific Reports, 2023 - nature.com
The study of the relationship between type 2 diabetes mellitus (T2DM) disease and other
pathologies (comorbidities), together with patient age variation, poses a challenge for …

In silico drug repurposing carvedilol and its metabolites against SARS-CoV-2 infection using molecular docking and molecular dynamic simulation approaches

C Zhang, J Liu, Y Sui, S Liu, M Yang - Scientific Reports, 2023 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by the infection of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a significant impact on …

Ghosts of the past: Elemental composition, biosynthesis reactions and thermodynamic properties of Zeta P. 2, Eta B. 1.525, Theta P. 3, Kappa B. 1.617. 1, Iota B. 1.526 …

M Popovic, MP Pavlović, M Pavlović - Microbial Risk Analysis, 2023 - Elsevier
From the perspectives of molecular biology, genetics and biothermodynamics, SARS-CoV-2
is the among the best characterized viruses. Research on SARS-CoV-2 has shed a new …

Priority index for critical Covid-19 identifies clinically actionable targets and drugs

Z Zhang, S Wang, L Jiang, J Wei, C Lu, S Li… - Communications …, 2024 - nature.com
While genome-wide studies have identified genomic loci in hosts associated with life-
threatening Covid-19 (critical Covid-19), the challenge of resolving these loci hinders further …

[HTML][HTML] Beyond COVID-19 pandemic: Topology-aware optimization of vaccination strategy for minimizing virus spreading

F Petrizzelli, PH Guzzi, T Mazza - Computational and Structural …, 2022 - Elsevier
The mitigation of an infectious disease spreading has recently gained considerable attention
from the research community. It may be obtained by adopting sanitary measurements (eg …

Systematic guidelines for effective utilization of COVID-19 databases in genomic, epidemiologic, and clinical research

DY Seong, J Park, K Yi, D Hong - Viruses, 2023 - mdpi.com
The pandemic has led to the production and accumulation of various types of data related to
coronavirus disease 2019 (COVID-19). To understand the features and characteristics of …

[HTML][HTML] A novel local alignment algorithm for Multilayer networks

M Milano, P Cinaglia, PH Guzzi, M Cannataro - Informatics in Medicine …, 2024 - Elsevier
Multilayer Network (MN) is a complex network comprising a set of graphs (also referred to as
layers) interconnected by edges or interlayer edges (or inter-edges) linking the nodes of …

Graph embedding techniques for predicting missing links in biological networks: An empirical evaluation

B Teji, S Roy, DS Dhami, D Bhandari… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Network science tries to understand the complex relationships among entities or actors of a
system through graph formalism. For instance, biological networks represent …

Strategies and Trends in COVID-19 Vaccination Delivery: What We Learn and What We May Use for the Future

G Tradigo, JK Das, P Vizza, S Roy, PH Guzzi, P Veltri - Vaccines, 2023 - mdpi.com
Vaccination has been the most effective way to control the outbreak of the COVID-19
pandemic. The numbers and types of vaccines have reached considerable proportions …

[HTML][HTML] Gene network modeling and pathway analysis of maize transcriptomes in response to Maize Iranian mosaic virus

A Ghorbani, M Rostami, K Izadpanah - Genomics, 2023 - Elsevier
Maize Iranian mosaic virus (MIMV, family Rhabdoviridae) is one of the factors limiting cereal
production in Iran. In the present study, we sought to find critical genes and key pathways …