From patterns to proteins: mass spectrometry comes of age in glomerular disease

S Sethi, JD Theis, LMP Palma… - Journal of the American …, 2024 - journals.lww.com
Laser capture microdissection and mass spectrometry (LCM/MS) is a technique that involves
dissection of glomeruli from paraffin-embedded biopsy tissue, followed by digestion of the …

Update on prognosis driven classification of pediatric AKI

M Patel, RA Gbadegesin - Frontiers in Pediatrics, 2022 - frontiersin.org
Acute kidney injury (AKI) affects a large proportion of hospitalized children and increases
morbidity and mortality in this population. Initially thought to be a self-limiting condition with …

Circulating TNF receptor levels are associated with estimated glomerular filtration rate even in healthy individuals with normal kidney function

T Gohda, M Murakoshi, T Shibata, Y Suzuki… - Scientific Reports, 2024 - nature.com
The association between serum tumor necrosis factor receptor (TNFRs: TNFR1, TNFR2)
levels and estimated glomerular filtration rate (eGFR) observed in patients with diabetes has …

Association of kidney tubule biomarkers with cardiac structure and function in the multiethnic study of atherosclerosis

N Wettersten, R Katz, JH Greenberg… - The American Journal of …, 2023 - Elsevier
Markers of glomerular disease, estimated glomerular filtration rate (eGFR) and albuminuria,
are associated with cardiac structural abnormalities and incident cardiovascular disease …

[HTML][HTML] Current and Novel Biomarkers of Progression Risk in Children with Chronic Kidney Disease

I Sandokji, Y Xu, M Denburg, S Furth, AG Abraham… - Nephron, 2024 - karger.com
Background: Due to the complexity of chronic kidney disease (CKD) pathophysiology,
biomarkers representing different mechanistic pathways have been targeted for the study …

[HTML][HTML] Plasma protein signatures for high on-treatment platelet reactivity to aspirin and clopidogrel in peripheral artery disease

G Baidildinova, AP Robles, V ten Cate… - Thrombosis …, 2023 - Elsevier
Background A significant proportion of patients with peripheral artery disease (PAD)
displays a poor response to aspirin and/or the platelet P2Y 12 receptor antagonist …

Derivation and independent validation of kidneyintelX. dkd: A prognostic test for the assessment of diabetic kidney disease progression

GN Nadkarni, S Stapleton, D Takale… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aims To develop and validate an updated version of KidneyIntelX (kidneyintelX. dkd) to
stratify patients for risk of progression of diabetic kidney disease (DKD) stages 1 to 3, to …

Urinary biomarkers of kidney tubule health and mortality in individuals with chronic kidney disease and diabetes mellitus

G Vasquez-Rios, R Katz, EB Levitan, M Cushman… - Kidney360, 2023 - journals.lww.com
Background: Kidney disease assessed by serum creatinine and albuminuria are strongly
associated with mortality in diabetes. These markers primarily reflect glomerular function …

[HTML][HTML] Systematic Review of Kidney Injury Biomarkers for the Evaluation of Chronic Kidney Disease of Uncertain Etiology

SE Claudel, SS Waikar - Kidney International Reports, 2024 - Elsevier
Introduction Chronic kidney disease of uncertain etiology (CKDu) is an incompletely defined
phenotype of CKD affecting young individuals mostly in agricultural communities in Central …

Association of Kidney Tubule Biomarkers With Cardiac Structure and Function in the Multiethnic Study of Atherosclerosis.

R Katz, J Greenberg, O Gutierrez, J Lima, M Sarnak… - 2023 - escholarship.org
Markers of glomerular disease, estimated glomerular filtration rate (eGFR) and albuminuria,
are associated with cardiac structural abnormalities and incident cardiovascular disease …