Cardiovascular disease is the main contributor to morbidity and mortality worldwide. Based
on its unique chemical features, the xanthophyll carotenoid astaxanthin is being proposed …

Heart failure (HF) and chronic kidney disease (CKD) co-exist, and it is estimated that about
50% of HF patients suffer from CKD. Although studies have been performed on the …

Background Few studies have prospectively evaluated the progression of chronic kidney
disease (CKD) in children and adolescents, as well as factors associated with progression …

Background Diabetic nephropathy (DN) is one of the major late complications of diabetes.
Treatment aimed at slowing down the progression of DN is available but methods for early …

Background The efficacy and benefits of telmisartan in cats with chronic kidney disease
(CKD) have not previously been reported. Hypothesis Long‐term treatment of cats with CKD …

Hematuria and proteinuria are common findings in primary care practice. Although the
American Academy of Pediatrics eliminated routine urine screening from its preventive care …

We have examined the pathogenic role of increased complement expression and activation
during kidney fibrosis. Here, we show that PDGFRβ-positive pericytes isolated from mice …

Although proteinuria is usually benign in the form of transient or orthostatic proteinuria,
persistent proteinuria may be associated with more serious renal diseases. Proteinuria may …

In contrast to adults where hypertension is a leading cause of chronic kidney disease, in
pediatrics, hypertension is predominantly a sequela, however, an important one that, like in …

Early identification of chronic kidney disease (CKD) provides an opportunity to implement
therapies to improve kidney function and slow progression. This chapter will first review the …