Haemonchosis in Sheep and Goats, Control Strategies and Development of Vaccines against Haemonchus contortus

I Adduci, F Sajovitz, B Hinney, K Lichtmannsperger… - Animals, 2022 - mdpi.com
Simple Summary Haemonchus contortus is the most pathogenic blood-feeding parasitic
nematode in sheep and goats, threatening animal welfare and causing tremendous …

Abridgement of Microbial Esterases and Their Eminent Industrial Endeavors

F Akram, T Fatima, I Shabbir, I Haq, R Ibrar… - Molecular …, 2024 - Springer
Esterases are hydrolases that contribute to the hydrolysis of ester bonds into both water-
soluble acyl esters and emulsified glycerol-esters containing short-chain acyl groups. They …

RNA‐seq analysis of parasitism by Intoshia linei (Orthonectida) reveals protein effectors of defence, communication, feeding and growth

EK Skalon, VV Starunov… - Journal of Experimental …, 2024 - Wiley Online Library
Orthonectida is a group of multicellular endoparasites of a wide range of marine
invertebrates. Their parasitic stage is a multinuclear shapeless plasmodium infiltrating host …

Identification of excretory and secretory proteins from Haemonchus contortus inducing a Th9 immune response in goats

M Liang, M Lu, MT Aleem, Y Zhang, M Wang, Z Wen… - Veterinary …, 2022 - Springer
Th9 cells have been shown to play crucial roles in anti-parasite immunity, pathogenic
microbe infection, and allergy. Previous studies have demonstrated that Haemonchus …

[HTML][HTML] Immunological characterization of chicken tumor necrosis factor-α (TNF-α) using new sets of monoclonal antibodies specific for poultry TNF-α

M Lu, Y Lee, C Li, HS Lillehoj - Developmental & Comparative Immunology, 2022 - Elsevier
Tumor necrosis factor-α (TNF-α) is a type II transmembrane protein with either membrane-
bound or soluble forms and is a prototypical member of the TNF superfamily. TNF-α is a …

In vitro characterization of Haemonchus contortus trehalose-6-phosphate phosphatase and its immunomodulatory effects on peripheral blood mononuclear cells …

ZH Wen, XR Xie, MT Aleem, K Aimulajiang, C Chen… - Parasites & …, 2021 - Springer
Abstract Background Trehalose-6-phosphate phosphatase (TPP6) is a key enzyme in the
trehalose biosynthesis pathway. The accumulation of TPP6 inside the body is harmful to the …

The excretory–secretory antigen HcADRM1 to generate protective immunity against Haemonchus contortus

M Lu, X Tian, W Wang, Y Zhang, K Aimulajiang… - Parasitology, 2021 - cambridge.org
The prevention, treatment and control of Haemonchus contortus have been increasingly
problematic due to its widespread occurrence and anthelmintic resistance. There are very …

Single-Cell Transcriptomic Profiling Unveils Dynamic Immune Cell Responses during Haemonchus contortus Infection

W Wang, Z Jin, M Kong, Z Yan, L Fu, X Du - Cells, 2024 - mdpi.com
Background: Haemonchus contortus is a parasite widely distributed in tropical, subtropical,
and warm temperate regions, causing significant economic losses in the livestock industry …

[HTML][HTML] Identification and characterization of the receptors of a microneme adhesive repeat domain of Eimeria maxima microneme protein 3 in chicken intestine …

Y Zhang, M Lu, J Huang, X Tian, M Liang, M Wang… - Poultry Science, 2024 - Elsevier
Eimeria maxima microneme protein 3 (EmMIC3) is pivotal in the initial recognition and
attachment of E. maxima sporozoites to host cells. EmMIC3 comprises 5 tandem Type I …

Haemonchus contortus HcL6 promoted the Th9 immune response in goat PBMCs by activating the STAT6/PU.1/NF-κB pathway

M Liang, Y Zhang, M Wang, Z Wen, C Chen, Y Bu… - Veterinary …, 2023 - Springer
Th9 cells play a crucial role in parasite immunity. The development of Th9 cells is facilitated
by several cytokines. Key transcription factors, such as STAT6, STAT5, and PU. 1, are known …