Generic acquisition protocol for quantitative MRI of the spinal cord

J Cohen-Adad, E Alonso-Ortiz, M Abramovic… - Nature protocols, 2021 - nature.com
Quantitative spinal cord (SC) magnetic resonance imaging (MRI) presents many challenges,
including a lack of standardized imaging protocols. Here we present a prospectively …

Segmentation of the human spinal cord

B De Leener, M Taso, J Cohen-Adad… - … Resonance Materials in …, 2016 - Springer
Segmenting the spinal cord contour is a necessary step for quantifying spinal cord atrophy in
various diseases. Delineating gray matter (GM) and white matter (WM) is also useful for …

Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks

C Gros, B De Leener, A Badji, J Maranzano, D Eden… - Neuroimage, 2019 - Elsevier
The spinal cord is frequently affected by atrophy and/or lesions in multiple sclerosis (MS)
patients. Segmentation of the spinal cord and lesions from MRI data provides measures of …

Comparative neuroanatomy of the lumbosacral spinal cord of the rat, cat, pig, monkey, and human

A Toossi, B Bergin, M Marefatallah, B Parhizi… - Scientific Reports, 2021 - nature.com
The overall goal of this work was to create a high-resolution MRI atlas of the lumbosacral
enlargement of the spinal cord of the rat (Sprague–Dawley), cat, domestic pig, rhesus …

A new framework for investigating the biological basis of degenerative cervical myelopathy [AO Spine RECODE-DCM Research Priority Number 5]: mechanical stress …

BM Davies, O Mowforth, AA Gharooni… - Global Spine …, 2022 - journals.sagepub.com
Study Design Literature Review (Narrative) Objective To propose a new framework, to
support the investigation and understanding of the pathobiology of DCM, AO Spine …

Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers

J Cohen-Adad, E Alonso-Ortiz, M Abramovic, C Arneitz… - Scientific Data, 2021 - nature.com
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI
protocol that provides valuable metrics for assessing spinal cord macrostructural and …

Spinal cord volume loss: a marker of disease progression in multiple sclerosis

C Tsagkas, S Magon, L Gaetano, S Pezold… - Neurology, 2018 - AAN Enterprises
Objective Cross-sectional studies have shown that spinal cord volume (SCV) loss is related
to disease severity in multiple sclerosis (MS). However, long-term data are lacking. Our aim …

Association of pain and CNS structural changes after spinal cord injury

CR Jutzeler, E Huber, MF Callaghan, R Luechinger… - Scientific Reports, 2016 - nature.com
Traumatic spinal cord injury (SCI) has been shown to trigger structural atrophic changes
within the spinal cord and brain. However, the relationship between structural changes and …

Spinal cord lesions and atrophy in NMOSD with AQP4-IgG and MOG-IgG associated autoimmunity

C Chien, M Scheel, T Schmitz-Hübsch… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Background: Spinal cord (SC) affection is a hallmark symptom of neuromyelitis optica
spectrum disorders (NMOSD). Patients with aquaporin-4 (AQP4-IgG+) or myelin …

Tract‐specific and age‐related variations of the spinal cord microstructure: a multi‐parametric MRI study using diffusion tensor imaging (DTI) and inhomogeneous …

M Taso, OM Girard, G Duhamel, A Le Troter… - NMR in …, 2016 - Wiley Online Library
Being able to finely characterize the spinal cord (SC) microstructure and its alterations is a
key point when investigating neural damage mechanisms encountered in different central …