[HTML][HTML] Fundus-controlled perimetry (microperimetry): application as outcome measure in clinical trials

M Pfau, JK Jolly, Z Wu, J Denniss, EM Lad… - Progress in Retinal and …, 2021 - Elsevier
Fundus-controlled perimetry (FCP, also called 'microperimetry') allows for spatially-resolved
mapping of visual sensitivity and measurement of fixation stability, both in clinical practice as …

[HTML][HTML] AI-based monitoring of retinal fluid in disease activity and under therapy

U Schmidt-Erfurth, GS Reiter, S Riedl… - Progress in retinal and …, 2022 - Elsevier
Retinal fluid as the major biomarker in exudative macular disease is accurately visualized by
high-resolution three-dimensional optical coherence tomography (OCT), which is used …

Artificial intelligence: the unstoppable revolution in ophthalmology

D Benet, OJ Pellicer-Valero - Survey of ophthalmology, 2022 - Elsevier
Artificial intelligence (AI) is an unstoppable force that is starting to permeate all aspects of
our society as part of the revolution being brought into our lives (and into medicine) by the …

Progression of photoreceptor degeneration in geographic atrophy secondary to age-related macular degeneration

M Pfau, L von der Emde, L de Sisternes… - JAMA …, 2020 - jamanetwork.com
Importance Sensitive outcome measures for disease progression are needed for treatment
trials in geographic atrophy (GA) secondary to age-related macular degeneration (AMD) …

Machine learning methods for diagnosis of eye-related diseases: a systematic review study based on ophthalmic imaging modalities

Q Abbas, I Qureshi, J Yan, K Shaheed - Archives of Computational …, 2022 - Springer
Glaucoma, diabetic retinopathy, diabetic hypertension (DHR), Cataract, and age-related
macular degeneration are some of the most common and important retinal diseases. A …

Clinical perspectives and trends: microperimetry as a trial endpoint in retinal disease

Y Yang, H Dunbar - Ophthalmologica, 2021 - karger.com
Endpoint development trials are underway across the spectrum of retinal disease. New
validated endpoints are urgently required for the assessment of emerging gene therapies …

Type 1 choroidal neovascularization is associated with reduced localized progression of atrophy in age-related macular degeneration

M Pfau, PT Möller, SH Künzel, L von der Emde… - Ophthalmology …, 2020 - Elsevier
Purpose To investigate the association between the presence of type 1 choroidal
neovascularization (CNV) and the localized progression of atrophy in age-related macular …

Association of reading performance in geographic atrophy secondary to age-related macular degeneration with visual function and structural biomarkers

SH Künzel, M Lindner, J Sassen, PT Möller… - JAMA …, 2021 - jamanetwork.com
Importance As a disabling and frequent disease, geographic atrophy secondary to age-
related macular degeneration (AMD) constitutes an important study subject. Emerging …

Artificial intelligence in retinal imaging: current status and future prospects

KA Heger, SM Waldstein - Expert review of medical devices, 2024 - Taylor & Francis
Introduction The steadily growing and aging world population, in conjunction with
continuously increasing prevalences of vision-threatening retinal diseases, is placing an …

Emerging therapies and their delivery for treating age‐related macular degeneration

CN Thomas, DA Sim, WH Lee… - British journal of …, 2022 - Wiley Online Library
Age‐related macular degeneration (AMD) is the most common cause of blindness in the
Western world and is characterised in its latter stages by retinal cell death and …