One compelling challenge in the therapy of epilepsy is to develop anti-epileptogenic drugs
with an impact on the disease progression. The search for novel targets has focused …

It is now more than 15 years since the molecular structures of the major prostanoid receptors
were elucidated. Since then, substantial progress has been achieved with respect to …

Objectives N‐acetylcysteine (NAC) is a clinically approved thiol‐containing redox
modulatory compound currently in trials for many neurological and psychiatric disorders …

The high societal and individual cost of schizophrenia necessitates finding better, more
effective treatment, diagnosis, and prevention strategies. One of the obstacles in this …

Glutamate receptor-mediated excitatory neurotransmission plays a key role in neural
development, differentiation and synaptic plasticity. However, excessive stimulation of …

Glutamate is an essential excitatory neurotransmitter regulating brain functions. Excitatory
amino acid transporter (EAAT)‐2 is one of the major glutamate transporters expressed …

Generation of neurotoxic amyloid β peptides and their deposition along with neurofibrillary
tangle formation represent key pathological hallmarks in Alzheimer's disease (AD). Recent …

Generation and deposition of amyloid beta peptides and neurofibrillary tangle formation are
key mechanisms involved in AD pathogenesis. Recent evidence suggests that inflammatory …

Prostacyclin (PGI2) is a member of the prostanoid group of eicosanoids that regulate
homeostasis, hemostasis, smooth muscle function and inflammation. Prostanoids are …

Stroke is a multiphasic process in which initial cerebral ischemia is followed by secondary
injury from immune responses to ischemic brain components. Here we demonstrate that …