Background Peripheral nerve injury (PNI) is very common in clinical practice, which often
reduces the quality of life of patients and imposes a serious medical burden on society …

Safe and efficient provision of electrical stimulation (ES) for nerve repair and regeneration is
a problem that needs to be addressed. In this study, a silk fibroin/poly (vinylidene fluoride-co …

The failure of peripheral nerve regeneration is often associated with the inability to generate
a permissive molecular and cellular microenvironment for nerve repair. Autologous …

A challenging complication in patients with peripheral compressive neuropathy is
neuropathic pain. Excessive neuroinflammation at the injury site worsens neuropathic pain …

Spinal Muscular Atrophy (SMA) and Amyotrophic Lateral Sclerosis (ALS) are
neurodegenerative diseases which are characterized by the loss of motoneurons within the …

Background Epigenetic regulation by histone deacetylases (HDACs) in Schwann cells (SCs)
after injury facilitates them to undergo de-and redifferentiation processes necessary to …

Chronic neuropathic pain is caused by dysfunction of the peripheral nerves associated with
the somatosensory system. Mesenchymal stem cells (MSCs) have attracted attention as …

Peripheral nerve injuries significantly impact patients' quality of life and poor functional
recovery. Chitosan–ufasomes (CTS–UFAs) exhibit biomimetic features, making them a …

Introduction Compressive neuropathy, a common chronic traumatic injury of peripheral
nerves, leads to variable impairment in sensory and motor function. Clinical symptoms …

The age and sex of studied animals profoundly impact experimental outcomes in biomedical
research. However, most preclinical studies in mice use a wide-spanning age range from 4 …