Transcription factors are a group of proteins, which possess DNA-binding domains, bind to
DNA strands of promoters or enhancers, and initiate transcription of genes with cooperation …

Polo-like kinase 1 (PLK1) is a serine/threonine kinase with more than 600 phosphorylation
substrates through which it regulates many biological processes, including mitosis …

Simple Summary Neuropilin-1 (NRP1) is a transmembrane protein which has had recently
increased interest from cancer researchers. Liver cancer and colorectal cancer (CRC) are …

Purpose Cyclin-dependent kinase regulatory subunit 2 (CKS2) has an important function in
regulating cancer progression and cell cycle. This research aims to ascertain how CKS2 …

Pin1-directed prolyl isomerization is a central common oncogenic mechanism to drive
tumorigenic processes. However, the role of Pin1 in cellular autophagy is still poorly …

Pancreatic cancer is a malignancy with high mortality. In addition to the few symptoms until
the disease reaches an advanced stage, the high fatality rate is attributed to its rapid …

Background: Hepatocellular carcinoma (HCC) is the sixth incidence of cancer and the third
leading cause of cancer mortality in the world. Facing the ever-increasing population of HCC …

In contrast to other types of cancers, there is no available efficient pharmacological treatment
to improve the outcomes of patients suffering from major primary liver cancers, ie …

Context: Salvia miltiorrhiza (SM) is a commonly used herb in traditional Chinese medicine
(TCM) and has been used in the treatment of pancreatic cancer to relieve the symptom of …

Hepatocellular carcinoma (HCC) is a universal problem. The risk factors for HCC could
either be environmental or host-genetic-related. The polymorphism of both FOXP3 …