How is epigenetics predicted to contribute to climate change adaptation? What evidence do we need?

K McGuigan, AA Hoffmann… - … Transactions of the …, 2021 - royalsocietypublishing.org
Transgenerational effects that are interpreted in terms of epigenetics have become an
important research focus at a time when rapid environmental changes are occurring. These …

How predictable is adaptation from standing genetic variation? Experimental evolution in Drosophila highlights the central role of redundancy and linkage …

C Schlötterer - … Transactions of the Royal Society B, 2023 - royalsocietypublishing.org
Experimental evolution is well-suited to test the predictability of evolution without the
confounding effects of inaccurate forecasts about future environments. Most of the literature …

Genetic redundancy fuels polygenic adaptation in Drosophila

N Barghi, R Tobler, V Nolte, AM Jakšić, F Mallard… - PLoS …, 2019 - journals.plos.org
The genetic architecture of adaptive traits is of key importance to predict evolutionary
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …

Genetic mixing for population management: From genetic rescue to provenancing

AA Hoffmann, AD Miller, AR Weeks - Evolutionary Applications, 2021 - Wiley Online Library
Animal and plant species around the world are being challenged by the deleterious effects
of inbreeding, loss of genetic diversity, and maladaptation due to widespread habitat …

Quantifying selection with pool-seq time series data

T Taus, A Futschik, C Schlötterer - Molecular biology and …, 2017 - academic.oup.com
Allele frequency time series data constitute a powerful resource for unraveling mechanisms
of adaptation, because the temporal dimension captures important information about …

Local adaptation across a complex bioclimatic landscape in two montane bumble bee species

JM Jackson, ML Pimsler, KJ Oyen… - Molecular …, 2020 - Wiley Online Library
Understanding evolutionary responses to variation in temperature and precipitation across
species ranges is of fundamental interest given ongoing climate change. The importance of …

Rapid and repeated climate adaptation involving chromosome inversions following invasion of an insect

LJ Ma, LJ Cao, JC Chen, MQ Tang… - Molecular Biology …, 2024 - academic.oup.com
Following invasion, insects can become adapted to conditions experienced in their invasive
range, but there are few studies on the speed of adaptation and its genomic basis. Here, we …

A simple genetic basis of adaptation to a novel thermal environment results in complex metabolic rewiring in Drosophila

F Mallard, V Nolte, R Tobler, M Kapun, C Schlötterer - Genome biology, 2018 - Springer
Background Population genetic theory predicts that rapid adaptation is largely driven by
complex traits encoded by many loci of small effect. Because large-effect loci are quickly …

Comparative studies of critical physiological limits and vulnerability to environmental extremes in small ectotherms: how much environmental control is needed?

AA Hoffmann, CM Sgro - Integrative Zoology, 2018 - Wiley Online Library
Researchers and practitioners are increasingly using comparative assessments of critical
thermal and physiological limits to assess the relative vulnerability of ectothermic species to …

'Evolutionary poker': an agent‐based model of interactome emergence and epistasis tested against Lenski's long‐term E. coli experiments

RS Root‐Bernstein, MI Bernstein - The Journal of Physiology, 2024 - Wiley Online Library
A simple agent‐based model is presented that produces results matching the experimental
data found by Lenski's group for≤ 50,000 generations of Escherichia coli bacteria under …