DIC in pregnancy–pathophysiology, clinical characteristics, diagnostic scores, and treatments

O Erez, M Othman, A Rabinovich, E Leron… - Journal of blood …, 2022 - Taylor & Francis
Obstetrical hemorrhage and especially DIC (disseminated intravascular coagulation) is a
leading cause for maternal mortality across the globe, often secondary to underlying …

Postpartum haemorrhage: prevention and treatment

L Sentilhes, B Merlot, H Madar, F Sztark… - Expert review of …, 2016 - Taylor & Francis
Introduction: Postpartum hemorrhage (PPH) is one of the leading causes of maternal death
and severe maternal morbidity worldwide and strategies to prevent and treat PPH vary …

FIGO recommendations on the management of postpartum hemorrhage 2022

MF Escobar, AH Nassar, G Theron… - … of Gynecology & …, 2022 - Wiley Online Library
METHODS The recommendations were developed as a synthesis and update of evidence
from the literature. They are based on the FIGO Safe Motherhood and Newborn Health …

Tranexamic acid for the prevention of blood loss after cesarean delivery

L Sentilhes, MV Sénat, M Le Lous… - … England Journal of …, 2021 - Mass Medical Soc
Background Prophylactic administration of tranexamic acid has been associated with
reduced postpartum blood loss after cesarean delivery in several small trials, but evidence …

[HTML][HTML] Tranexamic acid for the prevention of blood loss after vaginal delivery

L Sentilhes, N Winer, E Azria, MV Sénat… - … England Journal of …, 2018 - Mass Medical Soc
Background The use of tranexamic acid reduces mortality due to postpartum hemorrhage.
We investigated whether the prophylactic administration of tranexamic acid in addition to …

Disseminated intravascular coagulation in pregnancy: insights in pathophysiology, diagnosis and management

O Erez, SA Mastrolia, J Thachil - American journal of obstetrics and …, 2015 - Elsevier
Disseminated intravascular coagulation (DIC) is a life-threatening situation that can arise
from a variety of obstetrical and nonobstetrical causes. Obstetrical DIC has been associated …

Epidemiology and definition of PPH worldwide

J Bláha, T Bartošová - Best Practice & Research Clinical Anaesthesiology, 2022 - Elsevier
Highlights•Poor PPH outcomes are considered preventable in many cases, and are often
attributed to delayed recognition or inappropriate treatment.•Currently used definitions of …

National and international guidelines for patient blood management in obstetrics: a qualitative review

R Shaylor, CF Weiniger, N Austin… - Anesthesia & …, 2017 - journals.lww.com
January 2017• Volume 124• Number 1 www. anesthesia-analgesia. org 217 (i) to identify,
evaluate, and manage anemia;(ii) reduce iatrogenic blood loss;(iii) optimize hemostasis; …

Postpartum hemorrhage revisited: new challenges and solutions

N Higgins, SK Patel, P Toledo - Current Opinion in …, 2019 - journals.lww.com
Although postpartum hemorrhage itself may not be preventable, early identification of blood
loss, and mobilization of resources may prevent adverse outcomes. Multidisciplinary …

[HTML][HTML] Safety and efficacy of tranexamic acid for prevention of obstetric haemorrhage: an updated systematic review and meta-analysis

M Franchini, C Mengoli, M Cruciani, V Bergamini… - Blood …, 2018 - ncbi.nlm.nih.gov
Background A number of clinical systematic review and meta-analysis have been published
on the use of tranexamic in the obstetric setting. The aim of this meta-analysis was to …