An energy budget for signaling in the grey matter of the brain

D Attwell, SB Laughlin - Journal of Cerebral Blood Flow & …, 2001 - journals.sagepub.com
Anatomic and physiologic data are used to analyze the energy expenditure on different
components of excitatory signaling in the grey matter of rodent brain. Action potentials and …

Shared and divergent principles of synaptic transmission between cortical excitatory neurons in rodent and human brain

CPJ de Kock, D Feldmeyer - Frontiers in Synaptic Neuroscience, 2023 - frontiersin.org
Information transfer between principal neurons in neocortex occurs through (glutamatergic)
synaptic transmission. In this focussed review, we provide a detailed overview on the …

The cost of cortical computation

P Lennie - Current biology, 2003 - cell.com
Electrophysiological recordings show that individual neurons in cortex are strongly activated
when engaged in appropriate tasks, but they tell us little about how many neurons might be …

Efficacy and connectivity of intracolumnar pairs of layer 2/3 pyramidal cells in the barrel cortex of juvenile rats

D Feldmeyer, J Lübke, B Sakmann - The Journal of physiology, 2006 - Wiley Online Library
Synaptically coupled layer 2/3 (L2/3) pyramidal neurones located above the same layer 4
barrel ('barrel‐related') were investigated using dual whole‐cell voltage recordings in acute …

[图书][B] Computational neuroscience: a comprehensive approach

J Feng - 2003 - taylorfrancis.com
How does the brain work? After a century of research, we still lack a coherent view of how
neurons process signals and control our activities. But as the field of computational …

Maturation of intrinsic and synaptic properties of layer 2/3 pyramidal neurons in mouse auditory cortex

AMM Oswald, AD Reyes - Journal of neurophysiology, 2008 - journals.physiology.org
We investigated the development of L2/3 pyramidal cell (PC) circuitry in juvenile mice from
postnatal day 10 (P10) to P29. Using whole cell recordings in an in vitro thalamocortical …

The kinetics of synaptic vesicle pool depletion at CNS synaptic terminals

T Fernández-Alfonso, TA Ryan - Neuron, 2004 - cell.com
During sustained action potential (AP) firing at nerve terminals, the rates of endocytosis
compared to exocytosis determine how quickly the available synaptic vesicle pool is …

Nicotinic modulation of glutamate and GABA synaptic transmission in hippocampal neurons

KA Radcliffe, JL Fisher, R Gray… - Annals of the New York …, 1999 - Wiley Online Library
Although the hippocampus expresses nicotinic acetylcholine receptors (nAChRs) and
receives cholinergic innervation, the functional roles of these receptors are not completely …

Activity-dependent recruitment of extrasynaptic NMDA receptor activation at an AMPA receptor-only synapse

BA Clark, SG Cull-Candy - Journal of Neuroscience, 2002 - Soc Neuroscience
We have identified an excitatory synapse in cerebellar molecular layer interneurons at which
the level of presynaptic activity determines the receptor type involved in the postsynaptic …

Spontaneous development of synchronous oscillatory activity during maturation of cortical networks in vitro

T Opitz, AD De Lima, T Voigt - Journal of neurophysiology, 2002 - journals.physiology.org
Recent studies have focused attention on mechanisms of spontaneous large-scale wavelike
activity during early development of the neocortex. In this study, we describe and …