Foreword This Journal feature begins with a case vignette highlighting a common clinical
problem. Evidence supporting various strategies is then presented, followed by a review of …

Proton pump inhibitors (PPIs) are used extensively for the treatment of gastric acid-related
disorders, often over the long term, which raises the potential for clinically significant drug …

Background Medication toxic effects and drug-related problems can have profound medical
and safety consequences for older adults and economically affect the health care system …

Objective: Older people experience more concurrent illnesses, are prescribed more
medications and suffer more adverse drug events than younger people. Many drugs …

Background Adverse events related to drugs occur frequently among inpatients, and many
of these events are preventable. However, few data are available on adverse drug events …

Background Adverse drug reactions (ADRs) represent a major cause of iatrogenic morbidity
and mortality in patient care. While a substantial body of work has been undertaken to …

Adverse drug events cause substantial morbidity and mortality, yet they remain
underappreciated and misunderstood. The terminology to describe errors and patient harm …

Study Objectives: We sought to document the degree of polypharmacy, the frequency of
adverse drug-related events (ADREs) leading to emergency department presentation that …

Background: The Beers criteria identify inappropriate use of medications in older adults. The
number of and risk for adverse events from these medications are unknown. Objective: To …

Abstract Introduction: STOPP (Screening Tool of Older Persons' potentially inappropriate
Prescriptions) is a new, systems-defined medicine review tool. We compared the …