Depression rates in young people have risen sharply in the past decade, especially in
females, which is of concern because adolescence is a period of rapid social, emotional …

Major depressive disorder (MDD) is a common, debilitating, phenotypically heterogeneous
disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …

Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

Major depressive disorder is a remarkably common and often severe psychiatric disorder
associated with high levels of morbidity and mortality. Patients with major depression are …

Copy number variations (CNVs) of the human 16p11. 2 genetic locus are associated with a
range of neurodevelopmental disorders, including autism spectrum disorder, intellectual …

Copy number variants (CNVs) are deletions and duplications of DNA sequence. The most
frequently studied CNVs, which are described in this review, are recurrent CNVs that occur …

Importance Psychotic experiences, such as hallucinations and delusions, are reported by
approximately 5% to 10% of the general population, although only a small proportion …

Obsessive–compulsive disorder (OCD) affects 1–2% of the population, and, as with other
complex neuropsychiatric disorders, it is thought that rare variation contributes to its genetic …

Copy number variants (CNVs) at specific loci have been identified as important risk factors
for several neuropsychiatric disorders, such as schizophrenia, autism spectrum disorder …

Neuropsychiatric disorders, such as autism spectrum disorder (ASD), attention deficit
hyperactivity disorder (ADHD), schizophrenia (SCZ), bipolar disorder (BIP), and major …