EGF, a veteran of wound healing: highlights on its mode of action, clinical applications with focus on wound treatment, and recent drug delivery strategies
K Shakhakarmi, JE Seo, S Lamichhane… - Archives of Pharmacal …, 2023 - Springer
Epidermal growth factor (EGF) has been used in wound management and regenerative
medicine since the late 1980s. It has been widely utilized for a long time and still is because …
medicine since the late 1980s. It has been widely utilized for a long time and still is because …
Essential factors, advanced strategies, challenges, and approaches involved for efficient expression of recombinant proteins in Escherichia coli
Producing recombinant proteins is a major accomplishment of biotechnology in the past
century. Heterologous hosts, either eukaryotic or prokaryotic, are used for the production of …
century. Heterologous hosts, either eukaryotic or prokaryotic, are used for the production of …
Continuous Production of Human Epidermal Growth Factor Using Escherichia coli Biofilm
M Li, Z Wang, M Zhou, C Zhang, K Zhi, S Liu… - Frontiers in …, 2022 - frontiersin.org
Increasing demand for recombinant proteins necessitates efficient protein production
processes. In this study, a continuous process for human epidermal growth factor (hEGF) …
processes. In this study, a continuous process for human epidermal growth factor (hEGF) …
Cationic Solid SMEDDS of Efavirenz for Improved Oral Delivery: Development by Central Composite Design, In Vitro and In Vivo Evaluation
Efavirenz (EFV) is an anti-HIV drug with high dose and 40% oral bioavailability (BA). The
aim was to improve the bioavailability by designing cationic solid SMEDDS. Solubility data …
aim was to improve the bioavailability by designing cationic solid SMEDDS. Solubility data …
Refolding of bioactive human epidermal growth factor from E. coli BL21 (DE3) inclusion bodies & evaluations on its in vitro & in vivo bioactivity
Human epidermal growth factor (hEGF) is a mitogenic protein widely used in pharmaceutical
and cosmetic industries, thus recombinant DNA technology has been applied to meet the …
and cosmetic industries, thus recombinant DNA technology has been applied to meet the …
Production of recombinant human epidermal growth factor in Escherichia coli: Strategic upstream and downstream considerations for high protein yield
The human epidermal growth factor (hEGF) is a powerful mitogen used in medical treatment
and cosmetics. However, the recovery of hEGF from natural sources is insufficient to meet …
and cosmetics. However, the recovery of hEGF from natural sources is insufficient to meet …
The effects of combined co-expression of groel/es and trigger factor chaperone towards Thermus thermophilus DNA polymerase enzyme expression on Escherichia …
IP Maksum, DF Utami, S Sriwidodo… - Journal of Applied …, 2024 - japsonline.com
The Thermus thermophilus (Tth) DNA polymerase enzyme, originating from the thermophilic
bacterium T. thermophilus, exhibits bifunctionally as both a DNA polymerase and a reverse …
bacterium T. thermophilus, exhibits bifunctionally as both a DNA polymerase and a reverse …
Overexpression of soluble recombinant Thermus thermophilus (Tth) DNA polymerase in Escherichia coli BL21 (DE3) using an MBP fusion tag as a solubility enhancer
Tth DNA polymerase is a thermostable enzyme derived from Thermus thermophilus and acts
as a DNA polymerase and reverse transcriptase. Escherichia coli is used for large-scale …
as a DNA polymerase and reverse transcriptase. Escherichia coli is used for large-scale …
An overview of culture conditions for recombinant protein expression in Escherichia coli
Escherichia coli is one of the most commonly used organisms for producing recombinant
protein. The recognized cell genome and well-known cell factory of the bacteria make it an …
protein. The recognized cell genome and well-known cell factory of the bacteria make it an …
Stabilization of eye drops containing autologous serum and recombinant human epidermal growth factor for dry eye syndrome
S Sriwidodo, ISK Syah, IP Maksum… - Journal of Advanced …, 2020 - journals.lww.com
Human epidermal growth factor (hEGF) and autologous serum are considered safer and
more effective in treating dry eye syndrome. However, suitable formulas and preparation …
more effective in treating dry eye syndrome. However, suitable formulas and preparation …