Low molecular-mass plasma proteins play a key role in health and disease. Cystatin C is an
endogenous cysteine proteinase inhibitor belonging to the type 2 cystatin superfamily. The …

Cathepsins B, H and L have been shown to participate in processes of tumor growth,
vascularization, invasion and metastasis. Their levels in tumor tissue extracts can provide …

Serine proteases, cysteine proteases, and matrix metalloproteinases (MMPs) are involved in
cancer cell invasion and metastasis. Recently, a recombinant bifunctional inhibitor (chCys …

The turnover and remodelling of extracellular matrix (ECM) is an essential part of many
normal biological processes including development, morphogenesis, and wound healing …

Role of cysteine endopeptidases in cancerogenesis steps: neoplastic transformation,
invasion and metastasis is reviewed and discussed. Positive correlation between tumor …

AIM: Cysteine peptidase (CP) and its inhibitor (CPI) are a matrix protease that may be
associated with colorectal carcinoma invasion and progression, and vitamin E is also a …

Background. The activity of autogenic proteolytic enzymes is regulated in vivo by autogenic
inhibitors. They play important roles in maintaining a balance in many processes in the …

La cistatina C es una proteína de bajo peso molecular, que se caracteriza porque se filtra
totalmente a nivel glomerular y se reabsorbe y metaboliza a nivel tubular. En medicina …

Compostos de rutênio são promissores no tratamento do câncer, sendo bem tolerados in
vivo, uma vez que são mais tóxicos que a cisplatina, sendo apropriados para aplicação …

As cisteíno proteases são conhecidas por desempenharem importante papel no
metabolismo proteico celulares, no processamento de pró-hormônios e pró-enzimas, e na …