Importance Pancreatic ductal adenocarcinoma (PDAC) is a relatively uncommon cancer,
with approximately 60 430 new diagnoses expected in 2021 in the US. The incidence of …

Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …

Pancreatic and colorectal cancers are often KRAS mutated and are incurable when tumor
DNA or protein persists or recurs after curative intent therapy. Cancer vaccine ELI-002 2P …

This statement was developed to promote international consensus on the definition of
borderline resectable pancreatic ductal adenocarcinoma (BR-PDAC) which was adopted by …

The American Joint Committee on Cancer (AJCC) Staging Manual represents the standard
for classifying patients with pancreas and hepatobiliary cancers, predicting prognosis, and …

The earlier diagnosis of cancer is one of the keys to reducing cancer deaths in the future.
Here we describe our efforts to develop a noninvasive blood test for the detection of …

Purpose: Immune checkpoint inhibition has been shown to generate profound and durable
responses in mismatch repair deficient (MMR-D) solid tumors and has elicited interest in …

Importance The recently released eighth edition of the American Joint Committee on Cancer
TNM staging system for pancreatic cancer seeks to improve prognostic accuracy but lacks …

Background The 8th edition of the AJCC staging system for pancreatic cancer incorporated
several significant changes. This study sought to evaluate this staging system and assess its …

Purpose: Although abundant myeloid cell populations in the pancreatic ductal
adenocarcinoma (PDAC) microenvironment have been postulated to suppress antitumor …