Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

Understanding the pathogenesis of an infectious disease is critical for developing new
methods to prevent infection and diagnose or cure disease. Adherence of microorganisms to …

Candida albicans and Staphylococcus aureus are often co-isolated in cases of biofilm-
associated infections. C. albicans can cause systemic disease through morphological switch …

Approximately two decades have passed since the description of the first gene in the
Candida albicans ALS (agglutinin-like sequence) family. Since that time, much has been …

The yeast Candida albicans has emerged as a major public health problem during the past
two decades. The spectrum of diseases caused by this species ranges from vaginal …

The fungus C. albicans uses adhesins to interact with human epithelial surfaces in the
processes of colonization and pathogenesis. The C. albicans ALS (agglutinin-like …

Despite the importance of fungal cell walls as the principle determinant of fungal
morphology and the defining element determining fungal interactions with other cells, few …

The ability of yeast cells to adhere to other cells or substrates is crucial for many yeasts. The
budding yeast Saccharomyces cerevisiae can switch from a unicellular lifestyle to a …

Flexible adaptation to the host environment is a critical trait that underpins the success of
numerous microbes. The polymorphic fungus Candida albicans has evolved to persist in the …

Two univalent subunit vaccines that are based on major virulence traits of Candida albicans
have completed Phase I clinical trials in recent years. Although it is hoped that at least one …