Endotoxin tolerance is defined as a reduced capacity of a cell to respond endotoxin
(lipopolysaccharide, LPS) challenge after an initial encounter with endotoxin in advance …

A model of the development and progression of chronic fatigue syndrome (myalgic
encephalomyelitis), the aetiology of which is currently unknown, is put forward, starting with …

The objective was to unravel the peripartum immune and metabolic changes associated
with metritis in Holstein cows. Holstein cows (n= 128) had blood collected at− 14, 0, 3, and 7 …

M1 and M2 macrophage phenotypes, which mediate proinflammatory and antiinflammatory
functions, respectively, represent the extremes of immunoregulatory plasticity in the …

Sepsis is a systemic inflammatory response that may be induced by trauma, infection,
surgery, and burns. With the aim of discovering novel treatment targets for sepsis, this …

Immunologically immature neonates suffer the highest incidence of paediatric sepsis.
Postnatal immunological maturation is characterized by a relatively hypo‐inflammatory …

Immunosuppression is the most commonly used concept to qualify the immune status of
patients with either sterile systemic inflammatory response syndrome (SIRS) or sepsis. In …

Although alveolar macrophages (AMs) play important roles in preventing and eliminating
pulmonary infections, little is known about their regulation in healthy animals. Since …

The oral microbiome, with a unique emphasis on Porphyromonas gingivalis has been
associated with a constellation of inflammatory diseases such as cardiovascular disease …

Endotoxin tolerance (ET) is a state of reduced responsiveness to endotoxin stimulation after
a primary bacterial insult. This phenomenon has been described in several pathologies …