The relationship between obesity and cognitive health and decline

L Dye, NB Boyle, C Champ, C Lawton - Proceedings of the nutrition …, 2017 - cambridge.org
The relationship between obesity and cognitive impairment is important given the globally
ageing population in whom cognitive decline and neurodegenerative disorders will carry …

Update on Alzheimer's disease therapy and prevention strategies

WV Graham, A Bonito-Oliva… - Annual review of …, 2017 - annualreviews.org
Alzheimer's disease (AD) is the primary cause of age-related dementia. Effective strategies
to prevent and treat AD remain elusive despite major efforts to understand its basic biology …

A comparison of the prevalence of dementia in the United States in 2000 and 2012

KM Langa, EB Larson, EM Crimmins… - JAMA internal …, 2017 - jamanetwork.com
Importance The aging of the US population is expected to lead to a large increase in the
number of adults with dementia, but some recent studies in the United States and other high …

[HTML][HTML] Obesity trajectories and risk of dementia: 28 years of follow-up in the Whitehall II Study

A Singh-Manoux, A Dugravot, M Shipley… - Alzheimer's & …, 2018 - Elsevier
Introduction We examined whether obesity at ages 50, 60, and 70 years is associated with
subsequent dementia. Changes in body mass index (BMI) for more than 28 years before …

The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies

E Pedditizi, R Peters, N Beckett - Age and ageing, 2016 - academic.oup.com
Scope: it has been suggested that overweight/obesity as a risk factor for incident dementia
differs between mid-life and later life. We performed a systematic review and meta-analysis …

Body mass index in midlife and late‐life as a risk factor for dementia: a meta‐analysis of prospective studies

KJ Anstey, N Cherbuin, M Budge, J Young - Obesity reviews, 2011 - Wiley Online Library
The relationship between body mass index (BMI)(in midlife and late‐life) and dementia was
investigated in meta‐analyses of 16 articles reporting on 15 prospective studies. Follow‐ups …

Overview and findings from the religious orders study

D A. Bennett, J A. Schneider… - Current Alzheimer …, 2012 - benthamdirect.com
The Religious Orders Study is a longitudinal clinical-pathologic cohort study of aging and
Alzheimer's disease (AD). In this manuscript, we summarize the study methods including the …

Higher risk of dementia in English older individuals who are overweight or obese

Y Ma, O Ajnakina, A Steptoe… - International journal of …, 2020 - academic.oup.com
Background Several risk factors contribute to dementia, but the role of obesity remains
unclear. This study investigated whether increased body weight or central obesity were …

Obesity-induced brain neuroinflammatory and mitochondrial changes

LO Schmitt, JM Gaspar - Metabolites, 2023 - mdpi.com
Obesity is defined as abnormal and excessive fat accumulation, and it is a risk factor for
developing metabolic and neurodegenerative diseases and cognitive deficits. Obesity is …

2003-2013: a decade of body mass index, Alzheimer's disease, and dementia

TL Emmerzaal, AJ Kiliaan… - Journal of Alzheimer's …, 2015 - content.iospress.com
The occurrence of obesity, commonly estimated using body mass index (BMI), and the most
common late-onset dementia, Alzheimer's disease (AD), are increasing globally. The year …