The relationship between obesity and cognitive health and decline
The relationship between obesity and cognitive impairment is important given the globally
ageing population in whom cognitive decline and neurodegenerative disorders will carry …
ageing population in whom cognitive decline and neurodegenerative disorders will carry …
Update on Alzheimer's disease therapy and prevention strategies
WV Graham, A Bonito-Oliva… - Annual review of …, 2017 - annualreviews.org
Alzheimer's disease (AD) is the primary cause of age-related dementia. Effective strategies
to prevent and treat AD remain elusive despite major efforts to understand its basic biology …
to prevent and treat AD remain elusive despite major efforts to understand its basic biology …
A comparison of the prevalence of dementia in the United States in 2000 and 2012
KM Langa, EB Larson, EM Crimmins… - JAMA internal …, 2017 - jamanetwork.com
Importance The aging of the US population is expected to lead to a large increase in the
number of adults with dementia, but some recent studies in the United States and other high …
number of adults with dementia, but some recent studies in the United States and other high …
[HTML][HTML] Obesity trajectories and risk of dementia: 28 years of follow-up in the Whitehall II Study
A Singh-Manoux, A Dugravot, M Shipley… - Alzheimer's & …, 2018 - Elsevier
Introduction We examined whether obesity at ages 50, 60, and 70 years is associated with
subsequent dementia. Changes in body mass index (BMI) for more than 28 years before …
subsequent dementia. Changes in body mass index (BMI) for more than 28 years before …
The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies
Scope: it has been suggested that overweight/obesity as a risk factor for incident dementia
differs between mid-life and later life. We performed a systematic review and meta-analysis …
differs between mid-life and later life. We performed a systematic review and meta-analysis …
Body mass index in midlife and late‐life as a risk factor for dementia: a meta‐analysis of prospective studies
KJ Anstey, N Cherbuin, M Budge, J Young - Obesity reviews, 2011 - Wiley Online Library
The relationship between body mass index (BMI)(in midlife and late‐life) and dementia was
investigated in meta‐analyses of 16 articles reporting on 15 prospective studies. Follow‐ups …
investigated in meta‐analyses of 16 articles reporting on 15 prospective studies. Follow‐ups …
Overview and findings from the religious orders study
D A. Bennett, J A. Schneider… - Current Alzheimer …, 2012 - benthamdirect.com
The Religious Orders Study is a longitudinal clinical-pathologic cohort study of aging and
Alzheimer's disease (AD). In this manuscript, we summarize the study methods including the …
Alzheimer's disease (AD). In this manuscript, we summarize the study methods including the …
Higher risk of dementia in English older individuals who are overweight or obese
Y Ma, O Ajnakina, A Steptoe… - International journal of …, 2020 - academic.oup.com
Background Several risk factors contribute to dementia, but the role of obesity remains
unclear. This study investigated whether increased body weight or central obesity were …
unclear. This study investigated whether increased body weight or central obesity were …
Obesity-induced brain neuroinflammatory and mitochondrial changes
LO Schmitt, JM Gaspar - Metabolites, 2023 - mdpi.com
Obesity is defined as abnormal and excessive fat accumulation, and it is a risk factor for
developing metabolic and neurodegenerative diseases and cognitive deficits. Obesity is …
developing metabolic and neurodegenerative diseases and cognitive deficits. Obesity is …
2003-2013: a decade of body mass index, Alzheimer's disease, and dementia
TL Emmerzaal, AJ Kiliaan… - Journal of Alzheimer's …, 2015 - content.iospress.com
The occurrence of obesity, commonly estimated using body mass index (BMI), and the most
common late-onset dementia, Alzheimer's disease (AD), are increasing globally. The year …
common late-onset dementia, Alzheimer's disease (AD), are increasing globally. The year …